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3020630

Andryc edited this page May 14, 2021 · 1 revision

3020630 - PROTEIN [MASS/VOLUME] IN SERUM OR PLASMA

Although there is a qualitative difference between total protein in plasma and serum, the QUANTITATIVE difference is small and probably not clinically significant, therefore, system of SER/PLAS is acceptable. The protein concentration that is reported in electrophoresis is the same as that reported routinely.[1]

Total protein levels may be higher or lower than average in the case of certain disorders, including: [2]

  • bone marrow disorders
  • edema (fluid buildup in the tissues)
  • hepatitis (liver infection)
  • HIV
  • inflammatory bowel disease
  • kidney disease
  • leukemia
  • liver disease
  • malnutrition

Normal ranges vary by age and gender. [3]

In the OMOP vocabulary 3020630 is a Standard Concept that represents the measurement PROTEIN [MASS/VOLUME] IN SERUM OR PLASMA

The recommended low and high values for each unit associated with 3020630 are below. These are not meant to be normal values. Rather, these are meant to be biologically plausible values. For example, it would be implausible to see a patient with a weight of 0 kg though a person could be 2.5 kg.

8713

In the OMOP vocabulary 8713 is a Standard Concept that represents the unit GRAM PER DECILITER

Plausible Low Value

0.001

Plausible High Value

15.0

Rationale

The range 0-15 was chosen based on values seen in real world data. There are a number of outliers seen in this measurement likely due to source data entry mis-types and/or meaurement mis-labeling. In the data reviewed more than 90% of data with this standard unit concept should be accounted for.

References

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