XBB.1.5.16 with ORF1a:T592I, ORF1a:V2203I, ORF1a:I2229V and S:F456L (35 seqs, USA)

[NkRMnZr]

Defining Mutations: XBB.1.5.16 > C2040T(ORF1a:T592I/nsp2_T412I) > G6872A(ORF1a:V2203I/nsp3_V1385I), A6950G(ORF1a:I2229V/nsp3_I1411V) > T16548C, T22928C(S:F456L)
Query: C2040T, T16548C, T22928C
Earliest seq: 2023-04-02 (EPI_ISL_17523596, Houston, Texas, USA)
Latest seq: 2023-07-23 (EPI_ISL_18075248, Albany, New York, USA)
Sampled Countries: USA (29; New York/8 with ex. France; Michigan/5; California/3, with ex. Japan; Texas/3; Arizona/2; Ohio/2; Delaware/1; Illinois/1; Maryland/1; Minnesota/1; New Jersey/1; Nevada/1)

Genomes:

EPI_ISL_17523596, EPI_ISL_17685734, EPI_ISL_17690278, EPI_ISL_17700408, EPI_ISL_17716703, EPI_ISL_17763587, EPI_ISL_17768613, EPI_ISL_17768659, EPI_ISL_17768662, EPI_ISL_17815204, EPI_ISL_17815208-17815209, EPI_ISL_17839195, EPI_ISL_17853380, EPI_ISL_17950920, EPI_ISL_17950986, EPI_ISL_17976617, EPI_ISL_17976899, EPI_ISL_17979155, EPI_ISL_17986707, EPI_ISL_17998588, EPI_ISL_18039614, EPI_ISL_18054076, EPI_ISL_18054660, EPI_ISL_18064438, EPI_ISL_18071304, EPI_ISL_18075248, EPI_ISL_18075274, EPI_ISL_18075276

UShER:
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_36d2f_3b1dd0.json?f_userOrOld=uploaded%20sample&label=id:node_7149808

[FedeGueli]

Cant compete: https://cov-spectrum.org/explore/World/AllSamples/Past3M/variants?aaMutations=Orf1b%3AD54N&nucMutations1=C2040T%2CT16548C%2CT22928C&analysisMode=CompareToBaseline&

[NkRMnZr]

Tracking updates:

08-13, 1 more from USA: EPI_ISL_18093755
08-18, 3 seqs from USA
08-30, 2 seqs from USA

[FedeGueli]

One more from Texas

[NkRMnZr]

08-18, 3 seqs from USA:
1 from Texas EPI_ISL_18098964
1 from Florida: EPI_ISL_18104289
1 from New York: EPI_ISL_18104490

[NkRMnZr]

08-30, 2 seqs from USA: EPI_ISL_18131299, EPI_ISL_18153003

[FedeGueli]

Very few sequences in august i m closing it now.