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FY.3.1 (XBB.1.22.1.3.1) sublineage with S:Q613H and S:D950N (10 seqs in Japan) #522

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HynnSpylor opened this issue Aug 2, 2023 · 5 comments
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Apparently slow It means that a lineage is accumulating sequences slowly not that it is intrinsically slow. S:613

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@HynnSpylor
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Defining mutations:
FY.3.1>G4109T (ORF1a:D1282Y)>C25669T (ORF3a:H93Y)>T17688C, G23401C (S:Q613H)

GISAID query: A22161G, G4109T, G23401C
Earliest seq: 2023-07-05 (Japan, EPI_ISL_18051378)
Most recent seq: 2023-07-12 (Japan, EPI_ISL_18051430)
Countries detected: Japan (7)

Usher Tree:
QQ截图20230802001445

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_8bcf_92bee0.json?c=gt-S_613

S:Q613H is popular in FK.1 and EG.1 nowadays. All seqs are from Fukuoka, Japan and the IDs are consecutive, hence they may be two infection chains.

Genomes:
EPI_ISL_18051378-18051379, EPI_ISL_18051381, EPI_ISL_18051426-18051427, EPI_ISL_18051429-18051430

@HynnSpylor
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2 more seqs from Japan
and I omitted that they also get S:D950N (which emerged in Delta lineages)

@HynnSpylor HynnSpylor changed the title FY.3.1 (XBB.1.22.1.3.1) sublineage with S:Q613H (7 seqs in Japan) FY.3.1 (XBB.1.22.1.3.1) sublineage with S:Q613H and S:D950N (9 seqs in Japan) Aug 7, 2023
@FedeGueli FedeGueli added the To be proposed Green light for proposal label Aug 7, 2023
@FedeGueli
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Please propose it.

@FedeGueli FedeGueli added Apparently slow It means that a lineage is accumulating sequences slowly not that it is intrinsically slow. and removed Rapid review needed To be proposed Green light for proposal labels Aug 20, 2023
@FedeGueli
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It seems to have slowed down . lets track it till the end of this month.

@HynnSpylor
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1 more seq but still in Fukuoka, Japan. It really slowed down.

@HynnSpylor HynnSpylor changed the title FY.3.1 (XBB.1.22.1.3.1) sublineage with S:Q613H and S:D950N (9 seqs in Japan) FY.3.1 (XBB.1.22.1.3.1) sublineage with S:Q613H and S:D950N (10 seqs in Japan) Aug 28, 2023
@FedeGueli
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Closing for now. ping me if it starts again to pop up.

@FedeGueli FedeGueli closed this as not planned Won't fix, can't repro, duplicate, stale Aug 28, 2023
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Apparently slow It means that a lineage is accumulating sequences slowly not that it is intrinsically slow. S:613
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