XBB.1.22* lineage tracker

[NkRMnZr]

XBB.1.22* Lineage Tracker

L455F

F456L

T478X

• XBB.1.22.1 > G28198T(ORF8:C102F) > G8174A(ORF1a:A2637T), T13195C > T16854C, T20625C, C22227T(S:A222V) > C17421T, C22995G(S:T478R), A23598G(S:N679R) [Query: G8174A, T16854C, C22995G, 3, Oct5]

Q613H

• FY.3.1 (XBB.1.22.1.3.1) sublineage with S:Q613H and S:D950N (10 seqs in Japan) sars-cov-2-variants/lineage-proposals#522 FY.3.1 > C25669T(ORF3a:H93Y) > T17688C, G23401C(S:Q613H) [Query: T17688C, G23401C, C25669T, 10, Aug28]

RBD Levels

Known Potential Growth Booster

• XBB.1.22.1 with S:T572I (71 seqs, mainly in Japan, 6 countries) sars-cov-2-variants/lineage-proposals#635 XBB.1.22.1 > C23277T(S:T572I)
• Multiple FY.5 (XBB.1.22.1.5) Lineages with S:T572I sars-cov-2-variants/lineage-proposals#929 FY.5 > A6019G > G8653C(ORF1a:M2796I), T9616C, T18408C > C23277T(S:T572I)
• FY.5 > A6019G > C23277T(S:T572I)

FCS & Flanking

• FY.3.1 with ORF1a:I1990V (nsp3_I1172V) and S:Q493L (22 seqs, China, USA) sars-cov-2-variants/lineage-proposals#665 FY.3.1 > A6233G(ORF1a:I1990V) > A23040T(S:Q493L)

Others

• XBB.1.22.1 > C925A(ORF1a:D220E), G2265A(ORF1a:C667Y), C23585A(S:Q675K) > A8072G(ORF1a:N2603D), C13115T, C18744T, A22784G(S:R408G) [Query: A22784G, G25423A, C27427A, 21 seqs, Sep27]
• XBB.1.22.1 > C925A(ORF1a:D220E), G2265A(ORF1a:C667Y), C23585A(S:Q675K) > G22785A(S:R408N) [Query: G2265A, C23585A, G22785A, 16 seqs , Oct2]
• Multiple XBB.1.22.1 lineages with S:R408X sars-cov-2-variants/lineage-proposals#410 FY.1.1 > G22785A(S:R408N) [Query: G22785A, G21809T, G18811A, 25 seqs, Sep26]
• FY.3.1 > C22713A(S:P384H) [Query: G4109T, T22191C, C22713A 32, Oct6]
• FY.5 > A6019G > A22784G(S:R408G), A29394T(N:K374M) [Query: A6019G, A22784G, 6 seqs , Aug30]
• FY.6 > C13620T > A23989C > G22785A(S:S408N) [Query: A23989C, C13620T, C2037T, 58, Sep27]

Large Undesignated Cluster

Local Prevalence

Designated

Inactive