GJ.1.2 sublineage gained S:N450D ( 5 sequences South Korea , US, Singapore, France )

[FedeGueli]

I spotted a little cluster of three sequences of GJ.1.2 with S:N450D in three different far countries so i think it is worth proposing it immediately also keeping in mind that GJ.1.2 with just S:P521S as RBD mutations has been able to compete very well with other fast lineages with more RBD mutations pointing to a likely superior intrinsic fitness.
S:N450D is predicted to be slighty advantageous for ACE2 binding :

Interestingly the sequence from South Korea gained S:T478R further.

Tree:
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_1cf8e_ac48c0.json?c=userOrOld&label=id:node_7086733

Defining mutations: GJ.1.2 >> > S:N450D (A22910G )

Gisaid Query: A12878G, A22910G, C1549T, C7819G

Samples 3
South Korea, Singapore, Virginia
EPI_ISL_17970035, EPI_ISL_17996318, EPI_ISL_17996677

[FedeGueli]

4th from France , 4 seqs 3 continents.

[NkRMnZr]

5th from Singapore, with S:T478R: EPI_ISL_18056566

[FedeGueli]

Designated GJ.1.2.1 via cov-lineages/pango-designation@9326c3a