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XBB.1.46 with S:T478Q and S:F486P (12 seqs, 4 countries) #272

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NkRMnZr opened this issue Jun 28, 2023 · 2 comments
Closed

XBB.1.46 with S:T478Q and S:F486P (12 seqs, 4 countries) #272

NkRMnZr opened this issue Jun 28, 2023 · 2 comments
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Convergent evolution Lineages with convergent mutations S:478

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@NkRMnZr
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NkRMnZr commented Jun 28, 2023

Defining Mutations: XBB.1.46 > A22994C(S:T478Q, on top of existing C22995A/S:T478K), T23018C(S:F486P, on top of existing T23019C/S:F486S)
Query: G3606T, A22994C
Earliest seq: 2023-05-05 (EPI_ISL_17671915, Hubei, China)
Latest seq: 2023-05-22 (EPI_ISL_17739865, Heilongjiang, China)
Sampled Countries: China (8, Heilongjiang/5, Jiangxi/2, Hubei/1), Indonesia (1), Malaysia (1)

Genomes: EPI_ISL_17671915, EPI_ISL_17717736, EPI_ISL_17739638, EPI_ISL_17739648, EPI_ISL_17739650, EPI_ISL_17739811, EPI_ISL_17739865, EPI_ISL_17794694, EPI_ISL_17794705, EPI_ISL_17835792

UShER:
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_3b7ed_c59cc0.json?c=gt-S_486&f_userOrOld=uploaded%20sample&showBranchLabels=all

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@FedeGueli FedeGueli added Convergent evolution Lineages with convergent mutations S:478 labels Jun 28, 2023
@NkRMnZr
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NkRMnZr commented Jul 4, 2023 •
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Tracking updates

Update 1: 23-07-03, 1 seq from Singapore EPI_ISL_17957391
Update 2: 23-07-11, 1 seq from Malaysia EPI_ISL_17975979

@NkRMnZr NkRMnZr changed the title XBB.1.46 with S:T478Q and S:F486P (10 seqs, 3 countries) XBB.1.46 with S:T478Q and S:F486P (10 seqs, 4 countries) Jul 4, 2023
@NkRMnZr NkRMnZr changed the title XBB.1.46 with S:T478Q and S:F486P (10 seqs, 4 countries) XBB.1.46 with S:T478Q and S:F486P (12 seqs, 4 countries) Jul 11, 2023
@NkRMnZr NkRMnZr mentioned this issue Jul 28, 2023
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@NkRMnZr
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NkRMnZr commented Jul 28, 2023

slow, tracking it privately

@NkRMnZr NkRMnZr closed this as not planned Won't fix, can't repro, duplicate, stale Jul 28, 2023
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