XBB.1* Lineage Tracker

[NkRMnZr]

XBB.1* Lineage Tracker

F486P

• XBB.1 [pre-ORF8:G8*] > C6628T, C29376T(N:P368L)> C3593T(ORF1a:L1110F) > T23018C(S:F486P) [Query: C6628T, C29376T, T23018C, 14, Aug21]
• XBB.1 [G27915T(ORF8:G8*)] > C5173T > C25693A(ORF3a:L101I) > C10189T, C14925T, A22994C(S:T478Q), T23018C(S:S486P), A28126G(ORF8:N78S) [Query: C5173T, A22994C, T23018C, 4, Aug02]
• XBB.1 [G27915T(ORF8:G8*)] > C9700T > C28087T(ORF8:A65V) > G2883A(ORF1a:C873Y) > T5098C, T23018C(S:F486P) [Query: G2883A, T5098C, T23018C, 22, Aug04]
• XBB.1 [G27915T(ORF8:G8*)] > C11020T > C4276T, G11312A(ORF1a:V3683I), C15763T, C18189T, C18877T, A22995C_rev(S:K478T_rev), T23018C(S:F486P), C25566T, G28681A, C29546T [Query: C18877T, C25566T, G28681A, Aug02] Russia/BA-RII-MH142086S/2023|EPI_ISL_18059825|2023-05-29
• XBB.1 [G27915T(ORF8:G8*)] > C11575T > G2407A, C5974T, A12130G, T23018C(S:F486P) [Query: G2407A, C5974T, A12130G, July10] DRC/INRB-DRC-0568/2023|EPI_ISL_17976349|2023-05-06
• XBB.1 [G27915T(ORF8:G8*)] > C15588A > C13554T > C24421T > G23120T(S:A520S), G26293A(E:V17I) > A5032G, T17385C > T23018C(S:F486P), C27657T [Query: C15588A, T23018C, C27657T, 19, Jul24]
• XBB.1 [G27915T(ORF8:G8*)] > C15810T > G5515T, G21786T(S:G75V) > T23018C(S:F486P), T28297C(ORF9b:I5T) [Query: G5515T, C15810T, T23018C, 6, Aug20] (Sibling to XBB.1.14)
• XBB.1 [G27915T(ORF8:G8*)] > C22530T(S:T323I) > G14622T > A16641G > C26681T > C64T, C7029T(ORF1a:S2255F), G8513A(ORF1a:V2750I), A10323G(ORF1a:K3353R), C18306T, A22005C(S:N148T), T23018C(S:S486P) [Query: G14622T, C22530T, A22005C, Aug22] South_Africa/NICD-N55997/2023|EPI_ISL_18125211|2023-06-23
• XBB.1 [G27915T(ORF8:G8*)] > C26013T > T23018C(S:F486P) [Query: T23018C, C26013T, G27915T, -C2395T, -A3662G, -C4898T, -T6130C, -T6886C, -T10204C, -G11071A, - T17124C, -C17859T, -T21847C, -G22205C, -T28297C, 6, Sep13]
• XBB.1 [G27915T(ORF8:G8*)] > A28540G(ORF9b:E86G) > G26199T > T25959C > C15237T > C11750T(ORF1a:L3829F) > C10702T > G6362A(ORF1a:A2033T) > T23018C(S:F486P) [Query: C15237T, T23018C, G26199T, 10, Sep22]
• XBB.1 [G27915T(ORF8:G8*) > C11956T] > C8606T(ORF1a:L2781F) > C26029A(ORF3a:Q213K) > T23018C(S:F486P) [Query: T23018C, C26029A, C8606T, C11956T, 18, Sep8]
• XBB.1 [G27915T(ORF8:G8*) > T13704C] > C26058T > C21843T(S:S94F) > T23018C(S:F486P) [Query: C21843T,T23018C,C26058T, 3, Feb28]
• XBB.1.9 [T28297C/ORF9b:I5T > C12789T/ORF1a:T4175I > G5720A/ORF1a:G1819S] > C11956T > T4579A > G20433T(ORF1b:M2322I), G21761T(S:A67S) > T23018C(S:F486P) [Query: G20433T, G21761T, T23018C, 11, July17]
• XBB.1.30 > C13704T_reversion > C12924T(ORF1a:P4220L) > C492A(ORF1a:A76D), C622T, C2062T, A3273T(ORF1a:Q1003L), C4782T(ORF1a:S1506L), T18660C, A21782G(S:N74D), A22790G(S:I410V), T23018C(S:F486P), A24942C(S:D1127A), C28603T [Query: T23018C, A21782G, A24942C, 1] Canada/NL-PHML-624457/2023|EPI_ISL_17651777|2023-05-02
• XBB.1.30 > C11020T > G21123T, G27572A(ORF7a:S60N) > C6636T(ORF1a:T2124I), A11740G, T23018C(S:F486P), C28634A(N:L121I) [Query: A11740G, T23018C, C28634A, 16, Feb22]
• XBB.1.30 > C11020T > C5654T > T23018C(S:F486P) [Query: C11020T, C5654T, T23018C, A21137G, 19, Sep21]
• XBB.1.33 > C11644T > C23683T, G27915T(ORF8:G8＊) [Query: C11644T, C23683T, G27915T, 23, Sep27]
• XBB.1.33 > C11644T > C27858T(ORF7b:Q35*) [Query: C11644T, C27858T, 23, Sep27]
• XBB.1.33 with S:L452R ORF1a:P1921S (nsp3_P1103S) ORF1a:R2875H (nsp4_R112H) (12 seqs, Italy and Spain) sars-cov-2-variants/lineage-proposals#464 XBB.1.33 > C11644T > T22153A > C6026T(ORF1a:P1921S) > C28657T > G8889A(ORF1a:R2875H), T22917G(S:L452R) [Query: G8889A, T22917G , C28657T, 13, Sep5]
• XBB.1.33 > C11644T > C27476T(ORF7a:T28I) > C9532A(ORF1a:F3089L) > G1957A, A2543G(ORF1a:T760A), A18735G, C22326T(S:S255F), T22928C(S:F456L), A25501G(ORF3a:I37V), A26021C(ORF3a:D210A) [Query: C22326T, T22928C, A25501G, 1] Singapore/R35MR202/2023|EPI_ISL_17724733|2023-05-24
• XBB.1.33 > C19698T > C6433T, G18762A(ORF1b:M1765I), G23048A(S:G496S) > C22995G(S:T478R), G25654A(ORF3a:V88I), C27393T [Query: G25654A, C27393T, C22995G, 1] Croatia/HZJZ_4202/2023|EPI_ISL_17796067|2023-05-12
• XBB.1.35 > G20134A(ORF1b:V2223I) > T23018C(S:F486P) [Query: T23018C, G20134A, C3811T, 19, Sep25]
• XBB.1.36 > A548G(ORF1a:I95V) > G4904T(ORF1a:D1547Y), A21137G(ORF1b:K2557R) > G14874A, G20208T(ORF1b:Q2247H), C21660T(S:T33I), A22629C(S:K356T), T23018C(S:S486P) [Query: A548G, G4904T, T23018C, 2, Sep05]
• XBB.1.46 with S:T478Q and S:F486P (12 seqs, 4 countries) sars-cov-2-variants/lineage-proposals#272 XBB.1.46 > A22994C(S:T478Q), T23018C(S:F486P) [Query: G3606T, A22994C, 12, July10]

R403K

• XBB.1 [G27915T(ORF8:G8*)] > G1535A(ORF1a:V424I) > C8772T(ORF1a:T2836I) > C22450G, A22473G(S:K304R) > C5055T(ORF1a:T1597I), C16111T, C17474A(ORF1b:T1336N), C18115T(ORF1b:H1550Y), C18555T, G19872T, C22458T(S:T299I), G22770A(S:R403K), T23042C(S:S494P), G25455T(ORF3a:K21N), C26907T, C28112T, A28992T(N:Q240L), C29802T [Query: C22458T, A22473G, G22770A, 08/07] Shanghai/SCDC-XG07-10836/2023|EPI_ISL_18074809|2023-07-20
• XBB.1.28 saltation with ORF1a:G2814S (nsp4_G51S), S:L461I, S:N556S and ORF7a:P34L (45 seqs, 5 countries) sars-cov-2-variants/lineage-proposals#493 XBB.1 [G27915T(ORF8:G8*)] > T4579A > G6850A, G8705A(ORF1a:G2814S), C11455T, T18351C, G22770A(S:R403K), C22943A(S:L461I), C23086T, A23229G(S:N556S), C27494T(ORF7a:P34L) [Query: G22770A, C22943A, A23229G, 8, Sep14]

Y453F

• XBB.1.9.4 > C14352A(ORF1b:D295E) > G9526T(ORF1a:M3087I), T28382C(N:S37P) > C6070T > A4984G, T10732C, C11665T, C20148T, G22346A(S:A262T), A22920T(S:Y453F), C22987T, A25592C(ORF3a:K67T), C28637A(N:P122T) [Query: G22346A, A22920T, C22987T, 3, Jul28]

RBD Levels

• XBB.1 [G27915T(ORF8:G8*)] > C18591A > G21538A(ORF1b:2691) > T10306C, T23030C(S:F490P) > C17172A, A19098G, G22604T(S:A348S) [Query: G21538A, G22604T, T23030C, 13, Aug02]