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KP.1.1+S:F59S,S:T572I (175 seqs,>20 countries) #1646

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Memorablea opened this issue Jun 24, 2024 · 14 comments
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KP.1.1+S:F59S,S:T572I (175 seqs,>20 countries) #1646

Memorablea opened this issue Jun 24, 2024 · 14 comments

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@Memorablea
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Memorablea commented Jun 24, 2024

KP.1.1(S:F456L,S:R346T)+S:F59S,S:T572I
GISAID Query:C2488T, C19172T, T21738C, C23277T, C26735T
(suggested query: C2488T, C19172T, T21738C,C23277T finds 17)

EPI_ISL ID:
EPI_ISL_19181923, EPI_ISL_19182161, EPI_ISL_19182250,
EPI_ISL_19183300, EPI_ISL_19186883-19186884, EPI_ISL_19192229,
EPI_ISL_19192783, EPI_ISL_19208041, EPI_ISL_19210331,
EPI_ISL_19210346, EPI_ISL_19210627

UshER Tree:
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/singleSubtreeAuspice_genome_1678_953e80.json?f_userOrOld=uploaded%20sample
image

Thanks for @FedeGueli and @aviczhl2 in #1632

@FedeGueli FedeGueli changed the title KP.1.1+S:F59S,S:T572I (12seqs) KP.1.1+S:F59S,S:T572I (17 seqs) Jun 24, 2024
@FedeGueli
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I ve added a query tha finds 17 samples: C2488T, C19172T, T21738C,C23277T

@FedeGueli FedeGueli added Convergent evolution Lineages with convergent mutations S:59 Convergent Trio 346/456/572 KP.1.1 and removed Convergent evolution Lineages with convergent mutations labels Jun 24, 2024
@Memorablea Memorablea changed the title KP.1.1+S:F59S,S:T572I (17 seqs) KP.1.1+S:F59S,S:T572I (17 seqs,4 countries) Jun 24, 2024
@Memorablea
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Memorablea commented Jun 24, 2024

I ve added a query tha finds 17 samples: C2488T, C19172T, T21738C,C23277T

Update UshER tree
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/singleSubtreeAuspice_genome_1678_953e80.json?f_userOrOld=uploaded%20sample
image

Please add the S: 27 tag @FedeGueli

@FedeGueli
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I ve added a query tha finds 17 samples: C2488T, C19172T, T21738C,C23277T

Update UshER tree https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/singleSubtreeAuspice_genome_1678_953e80.json?f_userOrOld=uploaded%20sample image

Please add the S: 27 tag @FedeGueli

S:27 is tricky especially from Singapore they read many times the deletion this way, have you checked the nucleotide sequence with the deletion?

@FedeGueli FedeGueli added the S:18 label Jun 24, 2024
@Memorablea
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USA+1 18

@Memorablea Memorablea changed the title KP.1.1+S:F59S,S:T572I (17 seqs,4 countries) KP.1.1+S:F59S,S:T572I (18 seqs,4 countries) Jun 28, 2024
@Memorablea
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USA+1 Ireland+1 20now

@Memorablea Memorablea changed the title KP.1.1+S:F59S,S:T572I (18 seqs,4 countries) KP.1.1+S:F59S,S:T572I (20 seqs,5 countries) Jun 30, 2024
@FedeGueli
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pls propose it

@Memorablea
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pls propose it

If I don't request it from the Pango repository, it can still be specified. isn't it?

@Mydtlwn
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Mydtlwn commented Jun 30, 2024

Yes, it will still be designated, but there is a difference in meaning between proposing and not proposing. For some historically significant strains, it will allow more people to better understand them. Meanwhile, the variant with two convergent mutations is more significant in that repository.

@Memorablea
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Yes, it will still be designated, but there is a difference in meaning between proposing and not proposing. For some historically significant strains, it will allow more people to better understand them. Meanwhile, the variant with two convergent mutations is more significant in that repository.

to cov-lineages/pango-designation#2676

@FedeGueli
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Yes, it will still be designated, but there is a difference in meaning between proposing and not proposing. For some historically significant strains, it will allow more people to better understand them. Meanwhile, the variant with two convergent mutations is more significant in that repository.

to cov-lineages/pango-designation#2676

thank you

@Memorablea
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34

@Memorablea
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Memorablea commented Jul 6, 2024

51

@xz-keg
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xz-keg commented Aug 15, 2024

Designated MU.1 via cov-lineages/pango-designation@7fb8081

@xz-keg xz-keg added this to the MU.1 milestone Aug 15, 2024
@FedeGueli
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FedeGueli commented Aug 15, 2024

FedeGueli referenced this issue in cov-lineages/pango-designation Aug 15, 2024
@FedeGueli FedeGueli changed the title KP.1.1+S:F59S,S:T572I (20 seqs,5 countries) KP.1.1+S:F59S,S:T572I (175 seqs,>20 countries) Aug 15, 2024
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