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JN.1 (BA.2.86.1.1) sublineage with S:Q183H (32 seqs in 7 countries) #1096

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HynnSpylor opened this issue Nov 20, 2023 · 11 comments
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JN.1 (BA.2.86.1.1) sublineage with S:Q183H (32 seqs in 7 countries) #1096

HynnSpylor opened this issue Nov 20, 2023 · 11 comments

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@HynnSpylor
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Defining mutations: JN.1>G22111T (S:Q183H)
GISAID query: G11727A, G22111T, T22926C
Earliest seq: 2023-10-25 (NY, US- EPI_ISL_18499187)
Most recent seq: 2023-11-06 (Canada- EPI_ISL_18504314)
Countries detected: US (3), Canada (3), Japan (2)

Usher Tree: (Usher shows S:I70V rev artefact)
QQ截图20231120205152
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_30b7c_afe8c0.json

Notice that S:Q183E is for XBB* lineages. Now JN.1+S:Q183H branch is circulating and we can track it for a time.

Genomes:
EPI_ISL_18499187, EPI_ISL_18499266, EPI_ISL_18504314, EPI_ISL_18505101, EPI_ISL_18513037, EPI_ISL_18517615, EPI_ISL_18520852, EPI_ISL_18520856

@FedeGueli FedeGueli changed the title JN.1 (BA.2.86.1.1) sublineage with S:Q183H (8 seqs in 3 countries) JN.1 (BA.2.86.1.1) sublineage with S:Q183H (10 seqs in 4 countries) Dec 1, 2023
@FedeGueli
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+2 Scotland

@HynnSpylor
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15 seqs now (Mainly in Scotland)

@HynnSpylor HynnSpylor changed the title JN.1 (BA.2.86.1.1) sublineage with S:Q183H (10 seqs in 4 countries) JN.1 (BA.2.86.1.1) sublineage with S:Q183H (15 seqs in 5 countries) Dec 4, 2023
@FedeGueli FedeGueli changed the title JN.1 (BA.2.86.1.1) sublineage with S:Q183H (15 seqs in 5 countries) JN.1 (BA.2.86.1.1) sublineage with S:Q183H (24 seqs in 7 countries) Dec 6, 2023
@FedeGueli FedeGueli added To be proposed Green light for proposal and removed Rapid review needed labels Dec 6, 2023
@FedeGueli
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24 now please propose it. @corneliusroemer ping growing lineage.

@corneliusroemer
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corneliusroemer commented Dec 6, 2023

It doesn't look like this is a single lineage - or at least Usher struggles with it.

I've got this on the radar but the biggest Usher branch is only around 12 sequences or so. We'll get there eventually but for now still a bit small and scattered on Usher tree.

@FedeGueli
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It doesn't look like this is a single lineage - or at least Usher struggles with it.

I've got this on the radar but the biggest Usher branch is only around 12 sequences or so. We'll get there eventually but for now still a bit small and scattered on Usher tree.

Oh thank you i didbt check the last sequences.

@FedeGueli
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@corneliusroemer i ve rechecked it is one lineage , there is a sequence in a branch with a suspicious S:T21R reversion but the rest clusters together today:
Schermata 2023-12-06 alle 23 39 34
https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_48a8a_f74c0.json?c=userOrOld&label=id:node_4498096

@FedeGueli FedeGueli changed the title JN.1 (BA.2.86.1.1) sublineage with S:Q183H (24 seqs in 7 countries) JN.1 (BA.2.86.1.1) sublineage with S:Q183H (27 seqs in 7 countries) Dec 8, 2023
@HynnSpylor
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HynnSpylor commented Dec 12, 2023

32 seqs now
I'll transfer it to main page
联想截图_20231213005442

@HynnSpylor HynnSpylor changed the title JN.1 (BA.2.86.1.1) sublineage with S:Q183H (27 seqs in 7 countries) JN.1 (BA.2.86.1.1) sublineage with S:Q183H (31 seqs in 7 countries) Dec 12, 2023
@HynnSpylor HynnSpylor changed the title JN.1 (BA.2.86.1.1) sublineage with S:Q183H (31 seqs in 7 countries) JN.1 (BA.2.86.1.1) sublineage with S:Q183H (32 seqs in 7 countries) Dec 12, 2023
@FedeGueli
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Thank you

@FedeGueli
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73 now @HynnSpylor please update. @corneliusroemer i think this is already worth a designation.

@FedeGueli FedeGueli added designated and removed To be proposed Green light for proposal labels Jan 9, 2024
@FedeGueli FedeGueli added this to the JN.1.9 milestone Jan 9, 2024
FedeGueli referenced this issue in cov-lineages/pango-designation Jan 9, 2024
@FedeGueli
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Designated JN.1.9 via cov-lineages/pango-designation@678e57c

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