GO filtering

We have a priority list of evidence codes. Currently:

inferred from biological aspect of descendant
inferred from biological aspect of ancestor
inferred from reviewed computational analysis
inferred from electronic annotation
inferred from expression pattern
non-traceable author statement
traceable author statement
inferred from sequence model
inferred from sequence or structural similarity
inferred from sequence orthology
inferred by curator

As a special case we also remove IPI without a "with".

See GOFilter.pm for the up-to-date list.

Annotations with evidence codes at the bottom are kept in preference to those nearer the top of the list.

• we iterate through the evidence codes above in order then:

  • for each annotation with that evidence code, delete the annotation if there is another annotation for the same gene with:

    • a more specific term
    • or same term but a different evidence code

  • if there are duplicate annotations (same term and gene) with that evidence code, delete all but one