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Add colapse_paralogs to merging function #198

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pamelacamejom opened this issue Sep 20, 2022 · 2 comments
Open

Add colapse_paralogs to merging function #198

pamelacamejom opened this issue Sep 20, 2022 · 2 comments
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enhancement New feature or request

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@pamelacamejom
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Hi Gerry,
I wonder if you could incorporate the "colapse_paralogs" step to the merging function. After merging, I find many issues when having paralogs in one of the merged pangenomes. It looks like this stops merging some clusters, even when they are the same gene with the same neighbours.

@gtonkinhill
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Hi, I will look into adding this in the future.
In the mean time I would suggest using the --merge_paralogs option.

@gtonkinhill gtonkinhill added the enhancement New feature or request label Sep 30, 2022
@revinici
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revinici commented Aug 8, 2024

I'm trying to decrease the runtime of panaroo by processing my input genomes in batches and then merging. However, I've noticed that specifying the --merge_paralogs flag causes the merge step to take much longer than when not specifying the flag. What does the --merge_paralogs flags do exactly and how does it compare to the colapse_paralogs step? I'm trying to determine if I can get away with not using the flag.

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