BQ.1.1.22 sublineage with S:S256P circulating in Uk 280 sequences

[FedeGueli]

Gisaid Query: T22328C,C913A

Defining mutations: BQ.1.1.22 > C913A > S:S256P ( T22328C)
Tree:

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_ac19_e18fa0.json?label=id:node_6474871

Sequences (all UK) : 55 ( 45 on Gisaid)
EPI_ISL_16285787
EPI_ISL_16286582
EPI_ISL_16281022
EPI_ISL_16108552
EPI_ISL_16280339
EPI_ISL_15681953
EPI_ISL_16257621
EPI_ISL_16286554
EPI_ISL_15939039
EPI_ISL_15938925
EPI_ISL_15925982
EPI_ISL_15580139
EPI_ISL_15580143
EPI_ISL_16108492
EPI_ISL_16053417
EPI_ISL_15960470
EPI_ISL_16142567
EPI_ISL_16212561
EPI_ISL_15630706
EPI_ISL_15681986
EPI_ISL_15926161
EPI_ISL_15926071
EPI_ISL_15801112
EPI_ISL_15760441
EPI_ISL_15681784
EPI_ISL_15896373
EPI_ISL_15681817
EPI_ISL_16212501
EPI_ISL_16108570
EPI_ISL_16095010
EPI_ISL_16108576
EPI_ISL_15681796
EPI_ISL_16281429
EPI_ISL_16212498
EPI_ISL_16281212
EPI_ISL_16108720
EPI_ISL_16213618
EPI_ISL_15910216
EPI_ISL_16281287
EPI_ISL_15681797
EPI_ISL_16281437
EPI_ISL_15925978
EPI_ISL_15681964
EPI_ISL_16212564

[FedeGueli]

it doesnt seem very fast , closing it .

[FedeGueli]

255seqs as today

[FedeGueli]

Reopening this one after its recent evolution proposed in #1715 by @agamedilab

[FedeGueli]

It seems quite fast lately i suggest a designation of this one @InfrPopGen cause its advantage versus parental BQ.1.1.22 is clear for the lineage proposed here:

and becomes very significant for its sublineage with S:257S proposed by @agamedilab in #1715

And the #1715 is not that far from XBB.1.5 in Uk:

Link to covspectrum comparison tool vs parental BQ.1.1.22
https://cov-spectrum.org/explore/United%20Kingdom/AllSamples/from%3D2022-12-15%26to%3D2023-03-04/variants?nextcladePangoLineage=BQ.1.1.22*&nucMutations1=T22328C%2CC913A&analysisMode=CompareToBaseline&

[InfrPopGen]

Thanks for submitting. We've added lineage ER.1 with 225 newly designated sequences, and 10 updated. Defining mutation T22328C (S:S256P) (following C913A).

[FedeGueli]

Thx @InfrPopGen