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Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (39 seqs as of 2023-03-30) #1444

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c19850727 opened this issue Dec 19, 2022 · 8 comments
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Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (39 seqs as of 2023-03-30) #1444

c19850727 opened this issue Dec 19, 2022 · 8 comments
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monitor currently too small, watch for future developments recombinant recombinant proposal

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@c19850727
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This is another BA.2.75*/BQ.1* sharing a very similar recombination pattern with #1393 and #1425 .

Description

Recombinant between: BA.2.75* and BQ.1* (with S:R346T)
Earliest sequence: 2022/10/19 (Korea)
Most recent sequence: 2022/12/13 (Italy)
Countries circulating: Korea (1/8), France (1/8), Germany (1/8), US-KS (1/8), New Caledocia (1/8), Italy (3/8)
Potential breakpoint: Spike NTD (22580-22939)

Mutation profile (private mutations are in yellow color):
image
Private mutations: C1376T (ORF1a:P371S), T11645C (ORF1a:F3794L), G14430T
GISAID and Cov-spectrum query: C1376T, T11645C, G14430T

Evidence

Usher tree:
image
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_3452e_f1d290.json?c=gt-nuc_1376&label=id:node_9067168

Genomes:
EPI_ISL_15609528, EPI_ISL_15968293, EPI_ISL_16061180, EPI_ISL_16153148, EPI_ISL_16166674, EPI_ISL_16166701-16166702, EPI_ISL_16168949
@thomasppeacock thomasppeacock added monitor currently too small, watch for future developments recombinant recombinant proposal labels Dec 19, 2022
@corneliusroemer
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This one notably has S:T430I

@FedeGueli
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11 sequences as today the last three uploads from Umbria Italy

@c19850727 c19850727 changed the title Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (8 seqs as of 2022-12-19) Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (11 seqs as of 2022-12-25) Dec 26, 2022
@FedeGueli
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12th sequence again from Umbria, Italy

@c19850727 c19850727 changed the title Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (11 seqs as of 2022-12-25) Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (12 seqs as of 2022-12-31) Jan 1, 2023
@FedeGueli
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14 as today

@c19850727 c19850727 changed the title Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (12 seqs as of 2022-12-31) Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (14 seqs as of 2023-01-05) Jan 7, 2023
@c19850727 c19850727 changed the title Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (14 seqs as of 2023-01-05) Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (15 seqs as of 2023-01-08) Jan 9, 2023
@c19850727 c19850727 mentioned this issue Jan 11, 2023
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@FedeGueli
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17 sequences as today. last two from Umbria It, and Occitaine Fr.

@c19850727 c19850727 changed the title Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (15 seqs as of 2023-01-08) Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (19 seqs as of 2023-01-16) Jan 16, 2023
@SlimEKDev
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SlimEKDev commented Jan 20, 2023 •
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We had another sequence clustering with them : EPI_ISL_16529593 from Bretagne (FRA), similar to EPI_ISL16061180.

sc2rf estimated the BP between 22600 and 22897.

@FedeGueli
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21 sequences as today last two samples from Umbria Italy

@c19850727 c19850727 mentioned this issue Jan 21, 2023
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@c19850727 c19850727 changed the title Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (19 seqs as of 2023-01-16) Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (21 seqs as of 2023-01-20) Jan 22, 2023
@ktmeaton ktmeaton mentioned this issue Jan 24, 2023
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@c19850727 c19850727 changed the title Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (21 seqs as of 2023-01-20) Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (24 seqs as of 2023-02-03) Feb 5, 2023
@c19850727 c19850727 mentioned this issue Feb 9, 2023
Closed
@c19850727 c19850727 changed the title Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (24 seqs as of 2023-02-03) Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (26 seqs as of 2023-02-10) Feb 10, 2023
@c19850727 c19850727 changed the title Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (26 seqs as of 2023-02-10) Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (28 seqs as of 2023-02-22) Feb 24, 2023
@c19850727 c19850727 changed the title Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (28 seqs as of 2023-02-22) Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (29 seqs as of 2023-03-04) Mar 5, 2023
@c19850727 c19850727 changed the title Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (29 seqs as of 2023-03-04) Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (32 seqs as of 2023-03-20) Mar 21, 2023
@c19850727 c19850727 changed the title Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (32 seqs as of 2023-03-20) Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (38 seqs as of 2023-03-26) Mar 27, 2023
@c19850727 c19850727 changed the title Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (38 seqs as of 2023-03-26) Another BA.2.75*/BQ.1* recombinant similar to #1393 and #1425 (39 seqs as of 2023-03-30) Mar 31, 2023
@c19850727
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44 sequences now but it seems it already stopped growing.

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@corneliusroemer @SlimEKDev @thomasppeacock @c19850727 @FedeGueli