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resource consumption increase since 2.0.1 #51

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seru71 opened this issue May 19, 2020 · 4 comments
Open

resource consumption increase since 2.0.1 #51

seru71 opened this issue May 19, 2020 · 4 comments

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@seru71
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seru71 commented May 19, 2020

First of all thank you for the great work with the cgpwgs pipeline. We have been using version 2.0.1 and consider moving to 2.1.0 now, mainly due to the ASCAT/Caveman bug, but also performance improvements.

In the test runs we noticed however a considerable increase in resources needed to complete the analysis:

  1. runtime jumped from ~24 to ~40 hrs on 32 threads
  2. memory consumption raised as well (can report on precise numbers if needed)

Is there a reason for such increase in resource use considering changes introduced in 2.1.0 (since 2.0.1)?

@keiranmraine
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keiranmraine commented May 19, 2020

Although performance enhancements were made to some elements of the container we later identified that the SNV post processing update for fragment based counting had some performance issues.

We have an improved version in the stand-alone containers but have not done a test cycle to release a new version of the combined containers.

There are 2 PRs of note:

I'll raise an item in our management meeting regarding an updated release and resource.

(edit: removed ye-olde-english style typo)

@seru71
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seru71 commented May 19, 2020 via email

@keiranmraine
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Would you mind providing information as to your project/institute?

@seru71
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seru71 commented May 19, 2020 via email

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