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Wrong REVEL score for nonsense variant #126

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sczakihl opened this issue Oct 13, 2023 · 2 comments · Fixed by #139
Closed

Wrong REVEL score for nonsense variant #126

sczakihl opened this issue Oct 13, 2023 · 2 comments · Fixed by #139
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@sczakihl
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Describe the bug
REVEL is depicted as -infinity / benign very strong for nonsense variant, where REVEL should not be available.

To Reproduce
Steps to reproduce the behavior:

  1. Go to 'https://reev.cubi.bihealth.org/variant/chr7:42007251:G:A/grch37'
  2. Click on '....'
  3. Scroll down to 'Precomputed Scores'
  4. See error

Expected behavior
No REVEL score should be displayed for nonsense variants. See e.g.:
https://reev.cubi.bihealth.org/variant/chr2:219747090:C:A/grch37

Screenshots
Wrong REVEL for chr7:42007251:G:A
grafik

What it should look like e.g. for chr2:219747090:C:A
grafik

@sczakihl sczakihl added the bug Something isn't working label Oct 13, 2023
@gromdimon gromdimon added this to the 0.1.0 milestone Oct 16, 2023
@gromdimon gromdimon linked a pull request Oct 17, 2023 that will close this issue
@gromdimon
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Previous solution didn't solve the problem

@gromdimon gromdimon reopened this Oct 17, 2023
@gromdimon
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Previous commet seems to be invalid due to testing an old version.

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