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Release 4.0
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fcyu committed Dec 19, 2023
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All notable changes to this project are documented in this file.

## 4.0 - 2023-12-XX
## 4.0 - 2023-12-19
- Implement new MSFragger-DDA+ mode, triggered when DDA data is annotated as `DDA+` (MSFragger parameter `data_type=3`). MSFragger will perform full isolation window search, identifying multiple co-fragmented peptides from chimeric DDA spectra. This mode significantly boosts the number of IDs compared to conventional DDA search.
- Implement detailed mass-offset search mode. Each specified mass offset can have their own modification sites, neutral losses, and diagnostic ions.
- Overhaul the mass calibration and parameter optimization procedure for DIA data
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