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Update the 4.0 changelog according to Alexey's modifications.
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fcyu committed Dec 16, 2023
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9 changes: 4 additions & 5 deletions CHANGELOG.md
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All notable changes to this project are documented in this file.

## 4.0 - 2023-12-XX
- Add `DDA+` data type: `data_type=3`. It significantly boosts the number of IDs compared to the DDA data type.
- Add support for the detailed mass-offset search. Mass-offsets can have their own modified sites, neutral losses, and diagnostic ions.
- Overhaul the mass calibration and parameter optimization for DIA data type
- Implement new MSFragger-DDA+ mode, triggered when DDA data is annotated as `DDA+` (MSFragger parameter `data_type=3`). MSFragger will perform full isolation window search, identifying multiple co-fragmented peptides from chimeric DDA spectra. This mode significantly boosts the number of IDs compared to conventional DDA search.
- Implement detailed mass-offset search mode. Each specified mass offset can have their own modification sites, neutral losses, and diagnostic ions.
- Overhaul the mass calibration and parameter optimization procedure for DIA data
- Significantly improve the ddaPASEF .d loading speed
- In the pin file, write all proteins in one column
- Extract and print isolation window sizes when checking the LC-MS files
- Add peptide length `< 8`, `8`, `[9, 30]`, and `> 30` Boolean scores to pin files
- Replace ‘peptide_length’ score with Boolean peptide length scores (length `< 8`, `8`, `[9, 30]`, and `> 30`) in pin files
- Remove `log10_kl_negative_1` and `log10_kl_negative_2` from the DDA pin file
- Remove `peptide_length` score from pin files
- Remove `add_topN_complementary` option
- Various bug fixes and improvements

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