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rliger Release v2.0.0

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@mvfki mvfki released this 21 Mar 01:16
· 43 commits to master since this release

rliger 2.0.0

  • Added ligerDataset class for per-dataset information storage, with inheritance for specific modalities
  • Added a number of plotting functions with clear function names and useful functionality
  • Added Leiden clustering method, now as default rather than Louvain
  • Added pseudo-bulk DEG method
  • Added DEG analysis with one-vs-rest marker detection in runMarkerDEG() and pairwise comparison in runPairwiseDEG()
  • Added gene name pattern for expression percentage QC metric
  • Added native Seurat object support for the core integration workflow
  • Added a documentation website built with pkgdown
  • Added new iNMF variant method, consensus iNMF (c-iNMF), in runCINMF(). Not stable.
  • Changed liger object class structure
  • Moved iNMF (previously optimizeALS()), UINMF (previously optimizeALS(unshared = TRUE)) and online iNMF (previously online_iNMF()) implementation to new package RcppPlanc with vastly improved performance. Now wrapped in runINMF(), runUINMF() and runOnlineINMF() respectively, and all can be invoked with runIntegration().
  • Updated H5AD support to match up with Python anndata package 0.8.0 specs
  • Renamed many function/argument names to follow camelCase style, original names are still available while deprecation warnings are issued