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PRS_GCK_t2d_family_analysis

PRS_analysis for T2D family analysis

This is the analysis repository which accompanies the manuscript for https://www.medrxiv.org/content/10.1101/2024.08.13.24311668v1.full-text

Directory Contents

01 create Array vcf data with merge 1kg data

02 pre imputation

03 check QC for kinship sex check etc.

04 post imputation pipeline with run prs computed

paper

Genotype-phenotype discrepancy among family members carrying a novel glucokinase mutation: insights into the interplay of GCK-MODY and insulin resistance
Shuhui Ji, Hua Shu, Hongqiang Zhao, Yuanyuan Ye, Xuan Liu, Shanshan Chen, Ying Yang, Wenli Feng, Jingting Qiao, Jinyang Zhen, Xiong Yang, Ziyue Zhang, Yu Fan, Yadi Huang, Qing He, Minxian Wang, Kunlin Wang, Ming Liu
doi: https://doi.org/10.1101/2024.08.13.24311668   

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