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GA.4 (XBB.1.17.1.4) small saltation with S:F186L, S:L585F and ORF1b:E1184D (14 seqs in Greece and Romania) #908

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HynnSpylor opened this issue Oct 2, 2023 · 2 comments

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@HynnSpylor
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Defining mutations:
GA.4>T3442C>T3055C, G8185A, G17019T (ORF1b:E1184D), T22118C (S:F186L), C23315T (S:L585F), G25009A, T26103C
GISAID query: C23315T, G25009A, T26103C
Earliest seq: 2023-08-08 (Greece- EPI_ISL_18314349)
Most recent seq: 2023-09-07 (Greece- EPI_ISL_18315044)
Countries detected: Greece (12), Romania (2)

Usher Tree: (Yellow for the issue, Blue for GA.4.1)
QQ截图20231002222618

The saltation branch is neighbored with GA.4.1 (another important saltation branch of GA.4).

Genomes:
EPI_ISL_18281784-18281785, EPI_ISL_18314349, EPI_ISL_18314472, EPI_ISL_18314790, EPI_ISL_18314811-18314813, EPI_ISL_18314897,
EPI_ISL_18314922, EPI_ISL_18314942-18314943, EPI_ISL_18314965, EPI_ISL_18315044

@HynnSpylor HynnSpylor changed the title GA.4 (XBB.1.17.1.4) small saltation with S:F186L, S:L585F (14 seqs in Greece and Romania) GA.4 (XBB.1.17.1.4) small saltation with S:F186L, S:L585F and ORF1b:E1184D (14 seqs in Greece and Romania) Oct 2, 2023
@FedeGueli
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Yes GA.4.1 emerged in a very undersampled area around Nigeria, now that is spreading its pace it is not far from HK.3 without any 455-456 mutation.

@FedeGueli
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Designated GA.4.3 via cov-lineages/pango-designation@516ee4a

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