XCR: GK.1.1/FU.1 recombinant(Flip+573+704+1266+Orf9b:5,55) in USA(20 seqs)

[xz-keg]

XBB.1.5.70+C13405T,
C23280T(S:T573I),C23673T(S:S704L), A24373C,G25045A(rev),A25359G(S:K1266R),A26708G, T27059C(rev),T28005C(Orf8:38 rev),T28297C(Orf9b:I5T),A28447G(Orf9b:N55S), T29386C

C23280T,C23673T from GK.1.1
C13405T from an American GK.1.1 branch
A24373C,G25045A(rev),A25359G(S:K1266R),A26708G, T27059C(rev),T28005C(Orf8:38 rev),T28297C(Orf9b:I5T),A28447G(Orf9b:N55S), T29386C from an American FU.1 branch

GK.1.1---FU.1
Breakpoint between 23674 and 24372

GISAID query: A24373C,A25359G,C23280T
No. of seqs: 5(USA-AK,NJ,VA,FL,WA)

First: EPI_ISL_18266013, FL, 2023-8-23
LAtest: EPI_ISL_18309323, VA airport, 2023-9-17

usher

This is the lower branch, the upper branch is #824

usher for FU.1 donor

[FedeGueli]

Ping @corneliusroemer another recombinant that seems fast.

@aviczhl2 please propose it once it gets 20 seqs

[FedeGueli]

17 now

[ryhisner]

There are two sequences from this lineage today with a 4-AA insertion—S:214_ESGL or ins_22204GAGTCAGGCTTA. Both also have an extraordinarily rare synonymous nucleotide mutation, T2548G. It's only been in 10 sequences ever, the most recent being from February 2021.

[corneliusroemer]

GK.1.1 donor is here:

[xz-keg]

GK.1.1 donor is here:

Thanks! I missed an additional mutation of C13405T.

[corneliusroemer]

The parents are now designated as GK.1.1.1 and FU.1.1.1

[FedeGueli]

Designated XCR