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GK.2+S:K356T 8 Seqs in UK and US #813

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krosa1910 opened this issue Sep 14, 2023 · 3 comments
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GK.2+S:K356T 8 Seqs in UK and US #813

krosa1910 opened this issue Sep 14, 2023 · 3 comments
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designated FLip = S:L455F / S:F456L S:356
Milestone
GK.2.3

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@krosa1910
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Mutations on top of GK.2: G16236A->A22629C (S:K356T)
Gisaid Inquiry: A22629C,G16236A,G23093A
Sequences: EPI_ISL_18161462, EPI_ISL_18209224, EPI_ISL_18227154,
EPI_ISL_18227161, EPI_ISL_18247664, EPI_ISL_18248767,
EPI_ISL_18248772
Earliest: EPI_ISL_18227161 2023-08-04, England
Latest: EPI_ISL_18248772 2023-09-02, England
Usher Tree: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_24e0_2890a0.json
5C16F4E9-D54D-4AAF-8AA7-AFA6C3F0BBDF
The top tree there

Note: I was replying to Fed in #805 about probably K356T being more useful in Flip context, so I searched for this.
Not to say it is particularly fast, as a month after initial spread with 7 seqs is not some amazing performance with "flip". But still an interesting variant to track.
@krosa1910
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krosa1910 commented Sep 16, 2023 •
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@FedeGueli May I get TeFLon for this combo？

@HynnSpylor HynnSpylor mentioned this issue Sep 16, 2023
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@FedeGueli FedeGueli changed the title GK.2+S:K356T 7 Seqs in UK and US GK.2+S:K356T 8 Seqs in UK and US Sep 17, 2023
@FedeGueli
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One more seq

FedeGueli referenced this issue in cov-lineages/pango-designation Sep 17, 2023
@corneliusroemer
Designate GK.2.3 (XBB.1.5.70.2.3, S:K356T, England/US-NY) with 11 seqs
5e55afa
@FedeGueli
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Designated GK.2.3

@FedeGueli FedeGueli added this to the GK.2.3 milestone Sep 17, 2023
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designated FLip = S:L455F / S:F456L S:356
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@FedeGueli @krosa1910