XCP: EG.5.1/JD.1.1 recombinant( 19 seqs, 4 countries)

[xz-keg]

JD.1.1+
C2334T, C3622T, G5720A, T6896C(rev),C9693T, A11537G, C12789T, T14085C(rev), T14189C(rev),C19185T

C2334T, G5720A,C9693T,,C12789T are from EG.5.1

Orf1a: A690V, G1819S, A3143V, I3758V, T4175I
Orf1b: V241A(rev)

C3622T,A11537G(Orf1a:I3758V) are from an European EG.5.1 branch.

C19185T is JD.1.1 branch specific.

EG.5.1--JD.1.1
Breakpoint between 14190 and 14633

GISAID query: C3622T,A11537G,C19185T
No. of seqs: 3(France 2 Denmark 1)

EPI_ISL_18210617,Denmark, 2023-8-21
EPI_ISL_18237406,18239722, France, 2023-8-28

usher

usher for EG.5.1-side donor

Edited from the EG.5.1 donor ie gets a NSP6 mutation: Orf1a:I3758V = NSP6_I189V
EDITED: Rapid picture of this recombinant:

[FedeGueli]

Please add AA changes, proposal without proper AA definition wont be accepted. We are here to make a public service and clear, short communication is of utmost importance.

[FedeGueli]

This has S:A475V too.

[xz-keg]

This has S:A475V too.

Yeah, this is JD.1.1 spike.

[FedeGueli]

no new samples piling on

[xz-keg]

+1 UK-CLIMB seq

[xz-keg]

+1 Italy

[corneliusroemer]

Just discovered this independently, that's a good sign that this is real and interesting! Thanks for having done the footwork, makes designation quick and easy!

[LilKitt]

I was unsure of this sequence, until the new ones were uploaded. Seems very fit.

[FedeGueli]

This grew to 19 maybe worth a designation too cc @corneliusroemer

[FedeGueli]

scratch that already designated better sleeping too much new things today!

[FedeGueli]

XCP