Recent singaporean GJ.1.2 sublineage gained the brand new Orf7b described by Ryan Hisner via out of frame Orf7b:F13- (13 seqs) #585
Labels
Deletions/Truncations/Frameshifted
Lineage showing any deletions or stop codons or TRS changes.
While checking the last batch from Singapore i noticed that also GJ.1.2 has gained the out of frame deletion at Orf7b:13 described by @ryhisner about FR.1 , XBC.1 and GP.1 (see here) and extended explanation >(here)
Luckily this out of frame deltion occured at the same time with a nuc/AA mutation so we can track it and see it on [USHER]:
Orf1a:T4418I (C13517T)
(https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_33ef6_4c81b0.json?c=userOrOld&label=id:node_7202734)
So defining mutations for this sublineage are:
GJ.1.2>> C7819G > Orf1b:S997P (T16456C) > Orf1a:T4418I (C13517T), Orf7b:F13del( 27795_27796del)
Gisaid Query : del27795_27796,G28209C,C13517T
Samples : 12 all from Singapore
EPI_ISL_17849968, EPI_ISL_17957199, EPI_ISL_17957352,
EPI_ISL_18006736-18006737, EPI_ISL_18015376, EPI_ISL_18056922-18056924,
EPI_ISL_18082823-18082824, EPI_ISL_18082828
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