FK.1.1.2 with S:A684V (32 seqs, Australia)

[NkRMnZr]

Defining Mutations: FK.1.1.2 > A28154T > C23613T (S:A684V)
Query: C23613T, A28154T, T23071G
Earliest seq: 2023-05-07 (EPI_ISL_17662942, South Australia)
Latest seq: 2023-07-05 (EPI_ISL_17999365, South Australia)
Sampled Countries: Australia (32, SA/30, Victoria/2)

Genomes:

EPI_ISL_17662942, EPI_ISL_17703912, EPI_ISL_17703923, EPI_ISL_17793456, EPI_ISL_17793464, EPI_ISL_17793523, EPI_ISL_17793534, EPI_ISL_17793593, EPI_ISL_17793613, EPI_ISL_17793768, EPI_ISL_17793833, EPI_ISL_17802450, EPI_ISL_17822449, EPI_ISL_17849437, EPI_ISL_17849542, EPI_ISL_17849554, EPI_ISL_17849608, EPI_ISL_17849633, EPI_ISL_17849643, EPI_ISL_17849646, EPI_ISL_17849655, EPI_ISL_17849702, EPI_ISL_17849720, EPI_ISL_17999365, EPI_ISL_17999981-17999982, EPI_ISL_18000023, EPI_ISL_18000041, EPI_ISL_18000097-18000098, EPI_ISL_18000210, EPI_ISL_18000213

UShER:
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_1f6da_d30410.json?f_userOrOld=uploaded%20sample&label=id:node_7388027

Trivia:

• Be aware of FK.1.1.2's T23071G branch, it is a S:V503 silent mutation, close to predicted hot spot H505, also may be something close to V503E or G504S/D that may be bad for certain potential antibody, according to Cao et al., 2022 https://doi.org/10.1016/j.celrep.2022.111845

[FedeGueli]

it seems slow ,no recent smaples closing for now