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Newly emerging XBB.1.16.1+orf1a:R542C+S:K97E in Bangladesh(28 seqs, 10 countries) #370

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xz-keg opened this issue Jul 9, 2023 · 8 comments
Closed

Newly emerging XBB.1.16.1+orf1a:R542C+S:K97E in Bangladesh(28 seqs, 10 countries) #370

xz-keg opened this issue Jul 9, 2023 · 8 comments
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designated New mutations Lineage with an unusual/new/interesting mutation Rapid review needed
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FU.5

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@xz-keg
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xz-keg commented Jul 9, 2023 •
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XBB.1.16.1+C17430T+A21851G,A17295G,C1889T(Orf1a:R542C,S:K97E)

GISAID query:A21851G,A17295G,C1889T
No. of seqs: 21(Australia 2 Bangladesh 6 Finland 1 France 1 Italy 1 Singapore 5(1 from Georgia, 2 from Bangladesh) South Korea 5)

First: EPI_ISL_17647310, South Korea, 2023-4-23
Latest: EPI_ISL_17837565, Singapore, 2023-6-19

usher

屏幕截图 2023-07-09 184041

4/20 in Bangladesh today's batch(up from 2/57 in previous batches). and 2 Bangladesh->Singapore cases suggest that this is(or was in May-June) growing fast and have some share in Bangladesh.
@FedeGueli FedeGueli added the New mutations Lineage with an unusual/new/interesting mutation label Jul 9, 2023
@FedeGueli
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Thx for proposing it i ve seen the bangladesh seqs not the ones from Singapore, good catch

@xz-keg
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xz-keg commented Jul 18, 2023

+1 Sweden

@xz-keg xz-keg changed the title Newly emerging XBB.1.16.1+orf1a:R542C+S:K97E in Bangladesh(21 seqs, 8 countries) Newly emerging XBB.1.16.1+orf1a:R542C+S:K97E in Bangladesh(22 seqs, 9 countries) Jul 18, 2023
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xz-keg commented Jul 20, 2023

+2 July seqs of Singapore from Bangladesh.

@xz-keg xz-keg changed the title Newly emerging XBB.1.16.1+orf1a:R542C+S:K97E in Bangladesh(22 seqs, 9 countries) Newly emerging XBB.1.16.1+orf1a:R542C+S:K97E in Bangladesh(25 seqs, 9 countries) Jul 20, 2023
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xz-keg commented Jul 24, 2023 •
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+1 Singapore from Bangladesh, +1 Singapore local, +1 USA

@xz-keg xz-keg changed the title Newly emerging XBB.1.16.1+orf1a:R542C+S:K97E in Bangladesh(25 seqs, 9 countries) Newly emerging XBB.1.16.1+orf1a:R542C+S:K97E in Bangladesh(28 seqs, 10 countries) Jul 24, 2023
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xz-keg commented Jul 24, 2023

I think this lineage may have a high prevalance in Bangladesh now. As 3/12 of the July seqs from Singapore/imported from Bangladesh belongs to this one.

@FedeGueli
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Agree.Please propose it.

@FedeGueli FedeGueli added the To be proposed Green light for proposal label Jul 25, 2023
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FedeGueli commented Jul 25, 2023 •
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S:97 was in the past was associated to neurological symptoms in pediatric ages but i am not sure how much solid it was found then

@xz-keg xz-keg mentioned this issue Jul 25, 2023
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@xz-keg xz-keg closed this as completed Jul 25, 2023
@FedeGueli FedeGueli added designated and removed To be proposed Green light for proposal labels Jul 27, 2023
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FU.5

@xz-keg xz-keg added this to the FU.5 milestone Dec 17, 2023
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