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XBB.1.5 with ORF1a:P971S (nsp3_P153S), ORF7a:Q94H and S:F456L (26 seqs, mainly in the USA, 5 countries) #279

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NkRMnZr opened this issue Jun 29, 2023 · 2 comments
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@NkRMnZr
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NkRMnZr commented Jun 29, 2023

Defining Mutations: [On top of XBB.1.5's T17124C > T23018C] > C3176T(ORF1a:P971S) > G17079A, T22930G(S:F456L), A27675C(ORF7a:Q94H), C29323T
Query: G17079A, T22930G, A27675C
Earliest seq: 2023-03-01 (EPI_ISL_17211530, Illinois, USA)
Latest seq: 2023-06-07 (EPI_ISL_17832663, England, UK)
Sampled Countries: USA (19, Virginia/4, California/3, Illinois/3, Arizona/2, New York/2, Florida/1, Iowa/1, Michigan/1, North Carolina/1, New Jersey/1), France (3), UK (2, all England), Israel (1)

Genomes: EPI_ISL_17211530, EPI_ISL_17259243, EPI_ISL_17321326, EPI_ISL_17333376, EPI_ISL_17373355, EPI_ISL_17430054, EPI_ISL_17524669, EPI_ISL_17585436, EPI_ISL_17585469, EPI_ISL_17588599, EPI_ISL_17618893, EPI_ISL_17639662, EPI_ISL_17657627, EPI_ISL_17673604, EPI_ISL_17694227, EPI_ISL_17694228, EPI_ISL_17768067, EPI_ISL_17789201, EPI_ISL_17803716, EPI_ISL_17803985, EPI_ISL_17832663, EPI_ISL_17853897, EPI_ISL_17854730, EPI_ISL_17855048, EPI_ISL_17855890

UShER:
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_38869_d69ad0.json?f_userOrOld=uploaded%20sample

view from XBB.1.5 polytomy:
overview

details:
details

Trivia:

  • This lineage started early March in the USA, seemlingly dying off but now is on a second drive.
@NkRMnZr
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NkRMnZr commented Jul 4, 2023

Tracking updates

Update 1: 23-07-03, 1 seq from Curaçao EPI_ISL_17884954

@NkRMnZr NkRMnZr changed the title XBB.1.5 with ORF1a:P971S (nsp3_P153S), ORF7a:Q94H and S:F456L (25 seqs, mainly in the USA, 4 countries) XBB.1.5 with ORF1a:P971S (nsp3_P153S), ORF7a:Q94H and S:F456L (26 seqs, mainly in the USA, 5 countries) Jul 4, 2023
@FedeGueli
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it seems very slow (surprisingly) closing it for now.

@FedeGueli FedeGueli closed this as not planned Won't fix, can't repro, duplicate, stale Jul 22, 2023
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