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Recent KP.3.1.1 + S:A397V 43 sequences , 7 countries #1695

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FedeGueli opened this issue Jul 4, 2024 · 10 comments
Closed

Recent KP.3.1.1 + S:A397V 43 sequences , 7 countries #1695

FedeGueli opened this issue Jul 4, 2024 · 10 comments

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@FedeGueli
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FedeGueli commented Jul 4, 2024

KP.3.1.1 is actually the lineage growing faster globally with a global share around 10% in the very few last weeks
(6% outside Spain)
Now there is a recent small branch that got S:A397V , it is predicted to increase binding, lowering entry and improving slighty escape on a XBB.1.5 backbone by Bloom and Dadonaite
Screenshot 2024-07-04 alle 19 37 52
It was quite uncommon in the pandemic being sampled less than 400 times ( 1/4 of them in AY.4)
hence i propose it here

Defining mutations:
KP.3.1.1 > A7330T, S:A397V (C22752T)
Query: A7330T,C22752T
Samples: 4
Countries : Spain (2), Canada, Netherlands
IDs:EPI_ISL_19201724, EPI_ISL_19229209, EPI_ISL_19230347,
EPI_ISL_19231071
Tree
Screenshot 2024-07-04 alle 19 32 10
https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_1c48e_6d8440.json?c=userOrOld&label=id:node_11513231

@xz-keg xz-keg added DeFLuQE S:S31-+S:F456L+S:Q493E and removed S:31 labels Jul 5, 2024
@Huachuan1120
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The fifth sequence, from Switzerland, collected on June 18, EPI_ISL_19240398.

@FedeGueli FedeGueli changed the title Recent KP.3.1.1 + S:A397V 4 sequences , 3 countries Recent KP.3.1.1 + S:A397V 5 sequences , 4 countries Jul 6, 2024
@FedeGueli
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thank you

@FedeGueli FedeGueli changed the title Recent KP.3.1.1 + S:A397V 5 sequences , 4 countries Recent KP.3.1.1 + S:A397V 6 sequences , 5 countries Jul 8, 2024
@FedeGueli
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  • 1 Netherlands

@Huachuan1120
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  • 1 Netherlands

EPI_ISL_19254475, collected in Ireland on June 23, is the 7th sequence and the true fifth country.
IMG_0161

@FedeGueli FedeGueli changed the title Recent KP.3.1.1 + S:A397V 6 sequences , 5 countries Recent KP.3.1.1 + S:A397V 7 sequences , 5 countries Jul 9, 2024
@FedeGueli
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  • 1 Netherlands

EPI_ISL_19254475, collected in Ireland on June 23, is the 7th sequence and the true fifth country. IMG_0161

thx i wrongoed the count.

@Huachuan1120
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EPI_ISL_19258758, collected in England, UK on June 24. This is the eighth related sequence and the sixth country to report it.
IMG_0189

@FedeGueli FedeGueli changed the title Recent KP.3.1.1 + S:A397V 7 sequences , 5 countries Recent KP.3.1.1 + S:A397V 8 sequences , 6 countries Jul 12, 2024
@Huachuan1120
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On July 15, 8 new related sequences were submitted, including: Spain +2, Canada +6, bringing the total number of related sequences to 16.

@FedeGueli FedeGueli changed the title Recent KP.3.1.1 + S:A397V 8 sequences , 6 countries Recent KP.3.1.1 + S:A397V 16 sequences , 6 countries Jul 16, 2024
@FedeGueli FedeGueli changed the title Recent KP.3.1.1 + S:A397V 16 sequences , 6 countries Recent KP.3.1.1 + S:A397V 20 sequences , 6 countries Jul 24, 2024
@FedeGueli FedeGueli changed the title Recent KP.3.1.1 + S:A397V 20 sequences , 6 countries Recent KP.3.1.1 + S:A397V 26 sequences , 7 countries Jul 30, 2024
@FedeGueli
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26

@FedeGueli FedeGueli changed the title Recent KP.3.1.1 + S:A397V 26 sequences , 7 countries Recent KP.3.1.1 + S:A397V 29 sequences , 7 countries Aug 3, 2024
@FedeGueli
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most recent sequences are a canadian cluster so i m closing it

@FedeGueli FedeGueli closed this as not planned Won't fix, can't repro, duplicate, stale Aug 3, 2024
@xz-keg
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xz-keg commented Aug 15, 2024

Designated MC.7 via cov-lineages/pango-designation@610a2f5

@xz-keg xz-keg added this to the MC.7 milestone Aug 15, 2024
FedeGueli referenced this issue in cov-lineages/pango-designation Aug 15, 2024
@FedeGueli FedeGueli changed the title Recent KP.3.1.1 + S:A397V 29 sequences , 7 countries Recent KP.3.1.1 + S:A397V 43 sequences , 7 countries Nov 13, 2024
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