KP.3.1 with S:31del [18 seq, Basque, Extremadura,Madrid, Catalunya- Spain, Italy, USA, Wales]

[Sinickle]

Defining mutations:
KP.3.1 (G15372T, A19722G) > C12616T >Orf1a:S4286C (A13121T) S:S31del(del21653-55)

GISAID query: C12616T,A13121T

Credit to @FedeGueli for the query.

Earliest seq: April 30.
Recent seq: May 06.

Discussion: So far this is one of two KP.3 branches with S:31del. Although there are KP.3s with other S:31 mutations, S:31del appears to be the best mutation for that region, based on how it is performing in FLiRT variants. Since KP.3 is growing faster than FLiRT that do not have S:31del, it is likely that this sublineage will be faster than FLiRT with S:31del, which would make this a potential top variant today.

[FedeGueli]

Thank you @Sinickle for spotting and proposing. One thing to be noticed that doesnt make me certin if it will be as good as DeFLirt lineage is that S:S31del appear to be very performing when accompanied by R346T that is not present in KP.3 , but 493E could do the same job maybe or maybe even better we have just to wait to see there being very few studies on the 346-450-493 interactions.

[FedeGueli]

Just noticed it is a KP.3.1 sublineage now.

[FedeGueli]

+2 one new area in northern Spain: Badajoz Extremadura

[FedeGueli]

@Sinickle please propose it when it reaches 10seqs

[FedeGueli]

+1 Madrid

[JosetteSchoenma]

+2 Spain, Sevilla

[FedeGueli]

ping @corneliusroemer

[JosetteSchoenma]

+1 USA traveler from Italy

[JosetteSchoenma]

+1 Wales

[JosetteSchoenma]

+2 Spain, Basque

[FedeGueli]

17 now with a big upload from Basque country . It could be a hospital /long term care homes outbreak looking at metadata.

[FedeGueli]

+1 Catalunya

[xz-keg]

Designated KP.3.1.1 via cov-lineages/pango-designation@7b9dd23