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Improved support of Philips and GE features
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neurolabusc authored Mar 26, 2018
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46 changes: 46 additions & 0 deletions Philips/README.md
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## About

dcm2niix attempts to convert all DICOM images to NIfTI. The Philips enhanced DICOM images are elegantly able to save all images from a series as a single file. However, this format is necessarily complex. The usage of this format has evolved over time, and can become further complicated when DICOM are handled by DICOM tools (for example, anonymization, transfer which converts explicit VRs to implicit VRs, etc.).

This web page describes some of the strategies handle these images. However, users should be vigilant when handling these datasets. If you encounter problems using dcm2niix you can explore [https://github.com/rordenlab/dcm2niix competing DICOM to NIfTI converters] or [ [https://github.com/rordenlab/dcm2niix report an issue].

## Image Patient Position

The Image Patient Position (0020,0032) tag is required to determine the position of the slices with respect to each other (and with respect to the scanner bore). Philips scans often report two conflicting IPPs for each single slice: with one stored in the private sequence (SQ) 2005,140F while the other is in the public sequence. This is unusual, but is [ftp://medical.nema.org/medical/dicom/final/cp758_ft.pdf legal].

In practice, this complication has several major implications. First, not all software translate private SQs well. One potential problem is when the implicit VRs are saved as implicit VRs. This can obscure the fact that 2005,140F is an SQ. Indeed, some tools will convert the private SQ type as a "UN" unknown type and add another public sequence. This can confuse reading software.

Furthermore, in the real world there are many Philips DICOM images that ONLY contain IPP inside SQ 2005,140F. These situations appear to reflect modifications applied by a PACS to the DICOM data or attempts to anonymize the DICOM images (e.g. using simple Matlab scripts). Note that the private IPP differs from the public one by half a voxel. Therefore, in theory if one only has the private IPP, one can infer the public IPP location. Current versions of dcm2niix do not do this: the error is assumed small enough that it will not impact image processing steps such as coregistration.

In general it is recommended that you archive and convert DICOM images as they are created from the scanner. If one does use an export tool such as the excellent dcmtk, it is recommended that you preserve the explicit VR, as implicit VR has the potential of obscuring private sequence (SQ) tags. Be aware that subsequent processing of DICOM data can disrupt data conversion.

Therefore, dcm2niix will ignore the IPP enclosed in 2005,140F unless no alternative exists.

## Derived parametric maps stored with raw diffusion data

Some Philips diffusion DICOM images include derived image(s) along with the images. Other manufacturers save these derived images as a separate series number, and the DICOM standard seems ambiguous on whether it is allowable to mix raw and derived data in the same series (see PS 3.3-2008, C.7.6.1.1.2-3). In practice, many Philips diffusion images append [derived parametric maps](http://www.revisemri.com/blog/2008/diffusion-tensor-imaging/) with the original data. For example, ADC, Trace and Isotropic images can all be derived from the raw scans. As scientists, we want to discard these derived images, as they will disrupt data processing and we can generate better parametric maps after we have applied undistortion methods such as [Eddy and Topup](https://fsl.fmrib.ox.ac.uk/fsl/fslwiki/eddy/UsersGuide). The current version of dcm2niix uses the Diffusion Directionality (0018,9075) tag to detect B=0 unweighted ("NONE"), B-weighted ("DIRECTIONAL"), and derived ("ISOTROPIC") images. Note that the Dimension Index Values (0020,9157) tag provides an alternative approach to discriminate these images. Here are sample tags from a Philips enhanced image that includes and derived map (3rd dimension is "1" while the other images set this to "2").

```
(0018,9075) CS [DIRECTIONAL]
(0018,9089) FD 1\0\0
(0018,9087) FD 1000
(0020,9157) UL 1\1\2\32
...
(0018,9075) CS [ISOTROPIC]
(0018,9087) FD 1000
(0020,9157) UL 1\2\1\33
...
(0018,9075) CS [NONE]
(0018,9087) FD 0
(0020,9157) UL 1\1\2\33
```

## Diffusion Direction

Proper Philips enhanced scans use tag 0018,9089 to report the 3 gradient directions. However, in the wild, other files from Philips (presumably using older versions of Philips software) use the tags 2005,10b0, 2005,10b1, 2005,10b2. In general, dcm2niix will use the values that most closely precede the Dimension Index Values (0020,9157).

The current version of dcm2niix uses Dimension Index Values (0020,9157) to determine gradient number, which can also be found in (2005,1413). However, while 2005,1413 is always indexed from one, this is not necessarily the case for 0020,9157. For example, the ADNI DWI dataset for participant 018_S_4868 has values of 2005,1413 that range from 1..36 for the 36 directions, while 0020,9157 ranges from 2..37. The current version of dcm2niix compensates for this by re-indexing the values of 0020,9157 after all the volumes have been read.

## General variations

Prior versions of dcm2niix used different methods to sort images. However, these have proved unreliable The undocumented tags SliceNumberMrPhilips (2001,100A), NumberOfSlicesMrPhilips (2001,1018) are not always present. In theory, InStackPositionNumber (0020,9057) should be present in all enhanced files, but has not proved reliable (perhaps not in older Philips images or DICOM images that were modified after leaving the scanner). MRImageGradientOrientationNumber (2005,1413) is complicated by the inclusion of derived images.Therefore, current versions of dcm2niix do not depend on any of these.
30 changes: 21 additions & 9 deletions README.md
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Expand Up @@ -59,20 +59,32 @@ The batch processing binary `dcm2niibatch` is optional. To build `dcm2niibatch`

If you have any problems with the cmake build script described above or want to customize the software see the [COMPILE.md file for details on manual compilation](./COMPILE.md).

## Alternatives

- [Valerio Luccio's dinifti](http://cbi.nyu.edu/software/dinifti.php) is focused on conversion of Siemens data
- [dcm2nii](http://www.mccauslandcenter.sc.edu/mricro/mricron/dcm2nii.htm) is the predecessor of dcm2niix. It is deprecated for modern images, but does handle image formats that predate DICOM (proprietary Elscint, GE and Siemens formats).
- [Xiangrui Li's dicm2nii](http://www.mathworks.com/matlabcentral/fileexchange/42997-dicom-to-nifti-converter) is written in Matlab. The Matlab language makes this very scriptable.
- [dicom2nifti](https://github.com/icometrix/dicom2nifti) uses the scriptable Python wrapper utilizes the [high performance GDCMCONV](http://gdcm.sourceforge.net/wiki/index.php/Gdcmconv) executables.
- [MRtrix mrconvert](http://mrtrix.readthedocs.io/en/latest/reference/commands/mrconvert.html) is a useful general purpose image converter and handles DTI data well. It is an outstanding tool for modern Philips enhanced images.
- [Jolinda Smith's mcverter](http://lcni.uoregon.edu/%7Ejolinda/MRIConvert/) has great support for various vendors.
- [mri_convert](https://surfer.nmr.mgh.harvard.edu/pub/docs/html/mri_convert.help.xml.html) is part of the popular FreeSurfer package. In my limited experience this tool works well for GE and Siemens data, but fails with Philips 4D datasets.
- [SPM12](http://www.fil.ion.ucl.ac.uk/spm/software/spm12/) is one of the most popular tools in the field. It includes DICOM to NIfTI conversion. Being based on Matlab it is easy to script.

## Links

- [Dcm2Bids](https://github.com/cbedetti/Dcm2Bids) uses dcm2niix to create [BIDS](http://bids.neuroimaging.io/) datasets.
- [bidsify](https://github.com/spinoza-rec/bidsify) is a Python project that uses dcm2niix to convert DICOM and Philips PAR/REC images to the BIDS standard.
- [bidskit](https://github.com/jmtyszka/bidskit) uses dcm2niix to create [BIDS](http://bids.neuroimaging.io/) datasets.
- [boutiques-dcm2niix](https://github.com/lalet/boutiques-dcm2niix) is a dockerfile for installing and validating dcm2niix.
- [DAC2BIDS](https://github.com/dangom/dac2bids) uses dcm2niibatch to create [BIDS](http://bids.neuroimaging.io/) datasets.
- [heudiconv](https://github.com/nipy/heudiconv) can use dcm2niix to create [BIDS](http://bids.neuroimaging.io/) datasets.
- [nipype](https://github.com/nipy/nipype) can use dcm2niix to convert images.
- [pydcm2niix is a Python module for working with dcm2niix](https://github.com/jstutters/pydcm2niix).
- [Dcm2Bids](https://github.com/cbedetti/Dcm2Bids) uses dcm2niix to create [BIDS](http://bids.neuroimaging.io/) datasets.
- [dcm2niir](https://github.com/muschellij2/dcm2niir) R wrapper for dcm2niix/dcm2nii.
- [divest](https://github.com/jonclayden/divest) R interface to dcm2niix.
- [sci-tran dcm2niix](https://github.com/scitran-apps/dcm2niix) Flywheel Gear (docker).
- [neuro_docker](https://github.com/Neurita/neuro_docker) includes dcm2niix as part of a single, static Dockerfile.
- [boutiques-dcm2niix](https://github.com/lalet/boutiques-dcm2niix) is a dockerfile for installing and validating dcm2niix.
- [neurodocker](https://github.com/kaczmarj/neurodocker) generates [custom](https://github.com/rordenlab/dcm2niix/issues/138) Dockerfiles given specific versions of neuroimaging software.
- [dcm2niix_afni](https://afni.nimh.nih.gov/pub/dist/doc/program_help/dcm2niix_afni.html) is a version of dcm2niix included with the [AFNI](https://afni.nimh.nih.gov/) distribution.
- [divest](https://github.com/jonclayden/divest) R interface to dcm2niix.
- [heudiconv](https://github.com/nipy/heudiconv) can use dcm2niix to create [BIDS](http://bids.neuroimaging.io/) datasets.
- [MRIcroGL](https://github.com/neurolabusc/MRIcroGL) is available for MacOS, Linux and Windows and provides a graphical interface for dcm2niix. You can get compiled copies from the [MRIcroGL NITRC web site](https://www.nitrc.org/projects/mricrogl/).
- [neuro_docker](https://github.com/Neurita/neuro_docker) includes dcm2niix as part of a single, static Dockerfile.
- [NeuroDebian](http://neuro.debian.net/pkgs/dcm2niix.html) provides up-to-date version of dcm2niix for Debian-based systems.
- [neurodocker](https://github.com/kaczmarj/neurodocker) generates [custom](https://github.com/rordenlab/dcm2niix/issues/138) Dockerfiles given specific versions of neuroimaging software.
- [nipype](https://github.com/nipy/nipype) can use dcm2niix to convert images.
- [pydcm2niix is a Python module for working with dcm2niix](https://github.com/jstutters/pydcm2niix).
- [sci-tran dcm2niix](https://github.com/scitran-apps/dcm2niix) Flywheel Gear (docker).
10 changes: 7 additions & 3 deletions console/main_console.cpp
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Expand Up @@ -85,7 +85,7 @@ void showHelp(const char * argv[], struct TDCMopts opts) {
#else
#define kQstr ""
#endif
printf(" -f : filename (%%a=antenna (coil) number, %%c=comments, %%d=description, %%e echo number, %%f=folder name, %%i ID of patient, %%j seriesInstanceUID, %%k studyInstanceUID, %%m=manufacturer, %%n=name of patient, %%p=protocol,%s %%s=series number, %%t=time, %%u=acquisition number, %%v=vendor, %%x=study ID; %%z sequence name; default '%s')\n", kQstr, opts.filename);
printf(" -f : filename (%%a=antenna (coil) number, %%c=comments, %%d=description, %%e=echo number, %%f=folder name, %%i=ID of patient, %%j=seriesInstanceUID, %%k=studyInstanceUID, %%m=manufacturer, %%n=name of patient, %%p=protocol,%s %%s=series number, %%t=time, %%u=acquisition number, %%v=vendor, %%x=study ID; %%z=sequence name; default '%s')\n", kQstr, opts.filename);
printf(" -g : generate defaults file (y/n/o [o=only: reset and write defaults], default n)\n");
printf(" -h : show help\n");
printf(" -i : ignore derived, localizer and 2D images (y/n, default n)\n");
Expand Down Expand Up @@ -324,7 +324,11 @@ int main(int argc, const char * argv[])
if (invalidParam(i, argv)) return 0;
if ((argv[i][0] == 'n') || (argv[i][0] == 'N') || (argv[i][0] == '0')) //0: verbose OFF
opts.isVerbose = 0;
else if ((argv[i][0] == 'h') || (argv[i][0] == 'H') || (argv[i][0] == '2')) //2: verbose HYPER
else if ((argv[i][0] == 'o') || (argv[i][0] == 'O')) {//-1: experimental SQ skipping: 'O'ptimized!? faster, does not get confused with Philips tags
opts.isVerbose = -1;
printf(">> Experimental SQ skipping enabled\n");

} else if ((argv[i][0] == 'h') || (argv[i][0] == 'H') || (argv[i][0] == '2')) //2: verbose HYPER
opts.isVerbose = 2;
else
opts.isVerbose = 1; //1: verbose ON
Expand Down Expand Up @@ -356,7 +360,7 @@ int main(int argc, const char * argv[])
strcpy(opts.outdir,argv[i]);
} else if ((argv[i][1] == 'n') && ((i+1) < argc)) {
i++;
int seriesNumber = atoi(argv[i]);
float seriesNumber = atof(argv[i]);
if (seriesNumber < 0)
opts.numSeries = -1; //report series: convert none
else if ((opts.numSeries >= 0) && (opts.numSeries < MAX_NUM_SERIES)) {
Expand Down
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