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This repository is linked to the article: A first passage model of intravitreal drug delivery and residence time - influence of ocular geometry, individual variability, and injection location

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This repository is linked to the article: A first passage model of intravitreal drug delivery and residence time - influence of ocular geometry, individual variability, and injection location (currently on arxiv at https://arxiv.org/abs/2404.04086).

In the folder Code_figures_human_ensemble,

  • The file set_human_ensemble.ipynb compiles the geometries used for the human ensemble, and produces Figure 4 in the manuscript.
  • The file mfpt_human_ensemble.ipynb produces the MFPT results for the human ensemble geometries, corresponding to Figure 7b in the manuscript and Figure S1.5.1 in the Supplementary Information 1.
  • The file vr_exit_human_ensemble.ipynb produces the results of the proportion of drug exiting through the vitreous-retina interface, corresponding to Figure 9 in the manuscript.

In the folder Code_other_figures,

  • The file figure_mfpt_comparison_species.ipynb produces the results for the Figure 7a in the manuscript.
  • The file figure_density_over_time.ipynb, along with the data in Data/drug_qty_over_time_P2.csv, produce results for Figure S1.1.2 in the Supplementary Information 1.

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This repository is linked to the article: A first passage model of intravitreal drug delivery and residence time - influence of ocular geometry, individual variability, and injection location

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