This repository is linked to the article: A first passage model of intravitreal drug delivery and residence time - influence of ocular geometry, individual variability, and injection location (currently on arxiv at https://arxiv.org/abs/2404.04086).
In the folder Code_figures_human_ensemble
,
- The file
set_human_ensemble.ipynb
compiles the geometries used for the human ensemble, and produces Figure 4 in the manuscript. - The file
mfpt_human_ensemble.ipynb
produces the MFPT results for the human ensemble geometries, corresponding to Figure 7b in the manuscript and Figure S1.5.1 in the Supplementary Information 1. - The file
vr_exit_human_ensemble.ipynb
produces the results of the proportion of drug exiting through the vitreous-retina interface, corresponding to Figure 9 in the manuscript.
In the folder Code_other_figures
,
- The file
figure_mfpt_comparison_species.ipynb
produces the results for the Figure 7a in the manuscript. - The file
figure_density_over_time.ipynb
, along with the data inData/drug_qty_over_time_P2.csv
, produce results for Figure S1.1.2 in the Supplementary Information 1.