PBKtools

This is the repository for the PBKtools R package.

Contents:

• Metrics:
  • AAFE: Absolute Average-Fold Error
  • mape: Mean Absolute Percentage Error
  • mse_custom: Mean Squared Error
  • PBKOF: PBK Objective Function
  • rmse: Root Mean Squared Erros
  • WSSR: Weighted Sum of Squared Residuals
• AUC: Estimates the area under the curve
• ci_estimation: Estimates the confidence intervals of parameters in identifiability analysi
• Identifiability_analysis: Performs identifiability analysis on the parameters of a model
• PBPK_sensitivity: Performs local sensitivity analysis
• profile_likelihood: estimates the profile likelihood of a parameter of a model
• Weighting.func: Assigns weight values to the data points.

Installation

To install PBKtools package just run devtools::install_github('ntua-unit-of-control-and-informatics/PBK_modelling_tools/PBKtools').