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Merge pull request #47 from andrewjpage/cleanup_intermediate_files
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Cleanup intermediate files
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andrewjpage committed Aug 9, 2012
2 parents 07ac062 + 428f8fa commit e5d8433
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5 changes: 5 additions & 0 deletions ChangeLog
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2012-8-7 Andrew J. Page <[email protected]>
* Cleanup intermediate files by default
* Fix RF distance calculation and comparison

2012-4-24 Andrew J. Page <[email protected]>
* Initial beta testing version

15 changes: 10 additions & 5 deletions INSTALL
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The main executable should be in ./src/gubbins


These applications must be in your PATH:
FastTree http://www.microbesonline.org/fasttree/
RAxML (the full version) http://sco.h-its.org/exelixis/software.html
These applications must be already installed in your PATH:
FastTree (>=2.1.4) http://www.microbesonline.org/fasttree/
RAxML (>=7.2.8, the full version) http://sco.h-its.org/exelixis/software.html
Python 2.7

These Python packages must be in your PYTHONPATH:
Biopython (>=1.59)
Biopython (>=1.59)
DendroPy (>=3.11.1)
ReportLab (>= 2.5)


To run the application:
run_gubbbins.py my_alignment.aln
24 changes: 3 additions & 21 deletions README
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This application takes in a multi fasta alignment, finds all the SNP sites, then outputs the snp sites in the following formats:
VCF,
a multi fasta alignment,
relaxed phylib format.
This application takes in a multi fasta alignment and detects recombination regions.

The first sequence in the input file is taken as the reference.
To use it:
run_gubbins.py my_alignment.aln

To use:

multi_fasta_to_vcf my_file.aln


VCF
=====
This contains the position of each SNP in the reference sequence, and the occurance in each other sample.

Multi Fasta Alignment
=====
Similar to the input file but just containing the snpsites.

Relaxed Phylib format
=====
All the snpsites in a format for RAxML


1 change: 1 addition & 0 deletions VERSION
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0.1
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