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Is that still a major speed improvement compared to Samtools 1.8? IIRC, Samtools/HTSjdk etc werde updated and parallelized more (which they weren't when sambamba came out). So this could already be negligible... Thanks for the tip though!
May have a think of using sambamba to do sam/bam/cram operation like what I did in LncPipe
for sam->bam conversion
https://github.com/likelet/LncPipe/blob/master/LncRNAanalysisPipe.nf#L592
and bam sort
https://github.com/likelet/LncPipe/blob/master/LncRNAanalysisPipe.nf#L593
hope it helps
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