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Merge pull request #116 from nextstrain/subclades
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Subclades
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huddlej authored Aug 24, 2023
2 parents a52da18 + ce06291 commit 5e6eedc
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Showing 25 changed files with 640 additions and 1 deletion.
6 changes: 6 additions & 0 deletions config/h1n1pdm/auspice_config.json
Original file line number Diff line number Diff line change
Expand Up @@ -27,6 +27,11 @@
"title": "Clade",
"type": "categorical"
},
{
"key": "subclade",
"title": "Subclade",
"type": "categorical"
},
{
"key": "haplotype",
"title": "Derived haplotype",
Expand Down Expand Up @@ -119,6 +124,7 @@
},
"filters": [
"clade_membership",
"subclade",
"region",
"country",
"division",
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7 changes: 7 additions & 0 deletions config/h1n1pdm/auspice_config_who.json
Original file line number Diff line number Diff line change
Expand Up @@ -31,6 +31,12 @@
"menuItem": "clade",
"type": "discrete"
},
"subclade": {
"key": "subclade",
"legendTitle": "Subclade",
"menuItem": "subclade",
"type": "discrete"
},
"full_clade_membership": {
"key": "full_clade_membership",
"legendTitle": "Clade (long)",
Expand Down Expand Up @@ -108,6 +114,7 @@
],
"filters": [
"clade_membership",
"subclade",
"region",
"country",
"authors",
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45 changes: 45 additions & 0 deletions config/h1n1pdm/ha/subclades.tsv
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@@ -0,0 +1,45 @@
clade gene site alt
A HA1 129 D
A HA1 185 I

B HA1 187 A
B HA1 189 E
C HA1 156 K
C HA1 161 I

C.1 clade C
C.1 HA1 54 Q
C.1 HA1 186 T
C.1 HA1 189 E
C.1 HA1 308 R

C.1.1 clade C.1
C.1.1 HA1 142 R
C.1.1 HA1 137 S

C.1.1.1 clade C.1.1
C.1.1.1 HA1 216 A

C.1.2 clade C.1
C.1.2 HA1 48 P

C.1.3 clade C.1
C.1.3 HA1 73 T
C.1.3 HA1 141 E

C.1.4 clade C.1
C.1.4 HA1 94 N
C.1.4 HA1 85 P
C.1.4 HA1 321 I

C.1.5 clade C.1
C.1.5 HA1 185 V
C.1.5 nuc 863 G

C.1.6 clade C.1
C.1.6 HA1 70 I
C.1.6 HA1 169 R
C.1.6 HA1 211 Q



89 changes: 89 additions & 0 deletions config/h1n1pdm/na/subclades.tsv
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clade gene site alt
A NA 40 L
A NA 386 N

A.1 clade A
A.1 NA 40 I
A.1 NA 386 K
A.1 NA 264 I
A.1 NA 270 K

A.1.1 clade A.1
A.1.1 NA 449 D
A.1.1 NA 77 R

B clade A
B NA 40 I
B NA 386 K
B NA 51 K
B NA 452 I
B NA 74 S

B.1 clade B
B.1 NA 389 K

B.2 clade B
B.2 nuc 944 C
B.2 NA 52 N

B.2.1 clade B.2
B.2.1 NA 40 T
B.2.1 NA 72 N

B.3 clade B
B.3 NA 19 T
B.3 NA 66 F
B.3 NA 222 K

B.3.1 clade B.3
B.3.1 NA 16 A
B.3.1 nuc 830 C

B.3.1.1 clade B.3.1
B.3.1.1 NA 469 N

B.3.1.2 clade B.3.1
B.3.1.2 NA 366 N

C clade B.3
C NA 453 M
C nuc 452 A
C nuc 785 G

C.1 clade C
C.1 NA 264 T
C.1 nuc 881 A

C.2 clade C
C.2 NA 189 S

C.3 clade C
C.3 NA 216 V
C.3 NA 257 K
C.3 nuc 1172 G

C.4 clade C
C.4 NA 29 M
C.4 NA 80 M
C.4 NA 264 T
C.4 nuc 95 G


C.5 clade C
C.5 NA 469 N

C.5.1 clade C.5
C.5.1 NA 50 D
C.5.1 nuc 1313 G

C.5.1.1 clade C.5.1
C.5.1.1 NA 382 E

C.5.2 clade C.5
C.5.2 NA 13 V
C.5.2 nuc 1313 G

C.5.3 clade C.5
C.5.3 NA 200 N
C.5.3 nuc 1091 G

6 changes: 6 additions & 0 deletions config/h3n2/auspice_config.json
Original file line number Diff line number Diff line change
Expand Up @@ -27,6 +27,11 @@
"title": "Clade",
"type": "categorical"
},
{
"key": "subclade",
"title": "Subclade",
"type": "categorical"
},
{
"key": "haplotype",
"title": "Derived haplotype",
Expand Down Expand Up @@ -129,6 +134,7 @@
},
"filters": [
"clade_membership",
"subclade",
"region",
"country",
"division",
Expand Down
7 changes: 7 additions & 0 deletions config/h3n2/auspice_config_who.json
Original file line number Diff line number Diff line change
Expand Up @@ -49,6 +49,12 @@
"menuItem": "clade (long)",
"type": "discrete"
},
"subclade": {
"key": "subclade",
"legendTitle": "Subclade",
"menuItem": "subclade",
"type": "discrete"
},
"cTiter": {
"key": "cTiter",
"legendTitle": "Antigenic advance (tree model)",
Expand Down Expand Up @@ -120,6 +126,7 @@
],
"filters": [
"clade_membership",
"subclade",
"region",
"country",
"authors",
Expand Down
153 changes: 153 additions & 0 deletions config/h3n2/ha/subclades.tsv
Original file line number Diff line number Diff line change
@@ -0,0 +1,153 @@
clade gene site alt
A HA1 48 I
A HA1 45 N
A nuc 473 T
A.2 HA2 160 N
A.2 nuc 710 A
A.2 nuc 1535 G
A.3 HA1 128 A
A.3 HA1 142 G
A.3 nuc 1313 A
B HA1 3 I
B HA1 144 S
B HA1 159 Y
B HA1 160 T
B nuc 1277 A
C HA1 138 S
C HA1 159 S
C HA1 225 D
C HA1 326 R
C.1 HA1 3 I
C.1 HA1 91 N
C.1 HA1 144 K
C.1 HA1 193 S
C.1 HA2 149 M
A.3.2 HA1 62 K
A.3.2 HA1 83 R
A.3.2 HA1 261 Q
A.3.2 HA2 18 K
B.1 HA1 121 K
B.1 HA1 171 K
B.1 HA2 77 V
B.1 HA2 155 E
B.1.1 HA1 135 K
B.1.1 HA2 150 E
B.1.1 nuc 489 A
B.1.2 HA1 62 G
B.1.2 HA1 142 G
B.1.2 HA1 311 Q
B.1.2.1 HA1 62 G
B.1.2.1 HA1 135 K
B.1.2.1 HA1 142 G
B.1.2.1.1 HA1 128 A
B.1.2.1.1 HA1 138 S
B.1.2.1.1 HA1 186 D
B.1.2.1.1 HA1 190 N
D HA1 128 A
D HA1 137 F
D HA1 138 S
D HA1 193 S
E HA1 62 G
E HA1 131 K
E HA1 142 G
E HA2 200 I
E.1 HA1 83 E
E.1 HA1 94 N
E.1 HA2 193 M
F HA1 186 S
F HA1 193 S
F HA1 195 F
F HA1 198 P

F.1 clade F
F.1 HA1 171 N

F.1.1 clade F.1
F.1.1 HA1 48 T

G HA1 159 N
G HA1 160 I
G HA1 164 Q
G HA1 186 D
G HA1 190 N
G HA1 193 S
G HA1 195 F

G.1 clade G
G.1 HA1 156 S

G.1.1 clade G.1
G.1.1 HA1 53 G
G.1.1 HA1 104 G
G.1.1 HA1 276 R

G.1.1.1 clade G.1.1
G.1.1.1 HA1 157 I
G.1.1.1 HA1 262 N

G.1.1.2 clade G.1.1
G.1.1.2 HA1 299 K
G.1.1.2 HA1 140 K

G.1.2 clade G.1
G.1.2 HA1 53 G
G.1.2 HA1 201 K
G.1.2 HA1 219 Y

G.1.3 clade G.1
G.1.3 HA1 53 N
G.1.3 HA1 96 S
G.1.3 HA1 192 F

G.1.3.1 clade G.1.3
G.1.3.1 HA1 50 K
G.1.3.1 HA1 96 S

G.1.3.1.1 clade G.1.3.1
G.1.3.1.1 HA1 140 K

G.1.3.2 clade G.1.3
G.1.3.2 HA1 140 M
G.1.3.2 nuc 143 A


G.2 clade G
G.2 HA1 50 K
G.2 HA1 79 V
G.2 HA1 140 K

G.2.1 clade G.2
G.2.1 HA1 135 A
G.2.1 HA1 262 N

G.2.2 clade G.2
G.2.2 HA1 33 Q
G.2.2 HA1 262 N

G.3 clade G
G.3 HA1 205 F
G.3 HA1 212 T

G.4 clade G
G.4 HA1 62 R
G.4 HA1 156 Q
G.4 HA1 199 P



E.2 HA1 197 R
E.2 HA1 219 F
E.2 HA2 18 M
E.2 HA2 155 G
B.2 HA1 131 K
B.2 HA1 142 K
B.2 HA1 261 Q
B.3 HA1 121 K
B.3 HA1 144 K
B.4 HA1 31 S
B.4 HA1 53 N
B.4 HA1 144 R
B.4 HA1 171 K
B.4 HA1 192 T
B.4 HA1 197 H

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