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@tijyojwad tijyojwad released this 14 Nov 19:41
· 2446 commits to master since this release
v0.4.3
656766b

[0.4.3] (14 Nov 2023)

This release of Dorado introduces a new RNA m6A modified base model and initial support for poly(A)/poly(T) tail length estimation. It also introduces duplex performance enhancements and bug fixes to improve the stability of Dorado.

  • 803e3a7 - Add RNA m6A DRACH-context model
  • 0f282cd - Add poly(A)/poly(T) tail length estimation support for RNA and cDNA
  • 54e14ca - Add RNA read splitting
  • 2dc1f03 - Enable RNA adapter trimming
  • 80114c0 - Correctly update CIGAR and POS entries when trimming barcodes
  • 4b2025c - Add documentation for sample sheet support
  • 641cb08 - Reduce host memory footprint for duplex basecalling
  • 7c1c0f0 - Reduce working reads size, in particular for duplex.
  • 831f0a9 - Fix pairing check for split reads in duplex basecalling
  • b630567 - Account for split reads during progress tracking
  • 383fe02 - Update to Koi v0.4.1
  • 873c6b1 - Fix warnings about ONLY_C_LOCAL mismatches in PCH builds
  • 52cbabf - Encapsulate date dependency
  • 8fb8a4d - Disable Cutlass LSTM codepath for 128-wide LSTM layers because this kernel does not work
  • 6a9dad9 - Enable warnings as errors at build time
  • 5aaef31 - Address auto batchsize issues on unified memory Linux systems
  • 92b5a67 - Reduce compilation times
  • 062e3fd - Minor speed improvements to CPU beam search
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