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samuelecancellieri authored Dec 21, 2020
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CRISPRme is a web-based tool developed to perform genome-wide CRISPR/Cas predictive analysis and result assessment supporting genetic variant and personal genomes.

![fig_pipeline_breve-1](https://user-images.githubusercontent.com/32717860/53018798-93e99700-3453-11e9-85a9-89eba18b18bb.png)
<!--- ![fig_pipeline_breve-1](https://user-images.githubusercontent.com/32717860/53018798-93e99700-3453-11e9-85a9-89eba18b18bb.png) --->

The search engine integrated in CRISPRme is based on CRISPRitz (Cancellieri, Samuele, et al. "CRISPRitz: rapid, high-throughput and variant-aware in silico off-target site identification for CRISPR genome editing." Bioinformatics 36.7 (2020): 2001-2008.) to exploit the powerful and fast search methods in the package, integrated with a user friendly and comprehensive GUI allowing the user to inspect and analyze results with ease.

# CRISPRitz Installation and Usage
The two fastest way to use CRISPRitz is through the installation of Docker or Conda.
Here we summarize the steps to install CRISPRitz with Docker and Conda.
# CRISPRme Installation and Usage
The two fastest way to use CRISPRme is through the installation of Docker or Conda.
Here we summarize the steps to install CRISPRme with Docker and Conda.

## Installation (Phase 1)
**Conda installation (Linux and MacOS):**
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