Minimap2-2.10 (r761)
Changes to minimap2:
-
Optionally output the MD tag for compatibility with existing tools (#63,
#118 and #137). -
Use SSE compiler flags more precisely to prevent compiling errors on certain
machines (#127). -
Added option --min-occ-floor to set a minimum occurrence threshold. Presets
intended for assembly-to-reference alignment set this option to 100. This
option alleviates issues with regions having high copy numbers (#107). -
Exit with non-zero code on file writing errors (e.g. disk full; #103 and
#132). -
Added option -y to copy FASTA/FASTQ comments in query sequences to the
output (#136). -
Added the asm20 preset for alignments between genomes at 5-10% sequence
divergence. -
Changed the band-width in the ava-ont preset from 500 to 2000. Oxford
Nanopore reads may contain long deletion sequencing errors that break
chaining.
Changes to mappy, the Python binding:
- Fixed a typo in Align.seq() (#126).
Changes to paftools.js, the companion script:
-
Command sam2paf now converts the MD tag to cs.
-
Support VCF output for assembly-to-reference variant calling (#109).
This version should produce identical alignment for read overlapping, RNA-seq
read mapping, and genomic read mapping. We have also added a cook book to show
the variety uses of minimap2 on real datasets. Please see cookbook.md in the
minimap2 source code directory.
(2.10: 27 March 2017, r761)