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Crossroads in metabolic network from stoichiometrical and topological studies

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CONQUESTS

Conquests is Python3 tools to calculate :

  • topological crossraods (TC)
  • stoichiometrical crossroads (SC)
  • optimal_biomass based crossroads (OBC)

Required package:

  • pyasp (pip install pyasp)
  • cobrapy (pip install cobrapy)

Install

python setup.py install

usage

conquests.py [-h] -d DRAFTNET -b BIOMASS [-s SEED] [-t TARGET] [-l LIMIT] [-r REPOSITORY]

optional arguments:
  -h, --help            show this help message and exit
  -d DRAFTNET, --draftnet DRAFTNET
                        metabolic network in SBML format
  -b BIOMASS, --biomass BIOMASS
                        identifiant of biomass reaction
  -s SEED, --seed SEED  
			list of boundary seeds in SBML format for topological search
  -t TARGET, --target TARGET
                        list of biomass compounds in SBML format
  -l LIMIT, --limit LIMIT
                        limit to flux value to be considered as null
  -r REPOSITORY, --repository REPOSITORY
                        repository to store the answer-files (by default named answer_file in draft repository)

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