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Update README.md #19

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5 changes: 3 additions & 2 deletions README.md
Original file line number Diff line number Diff line change
Expand Up @@ -62,8 +62,9 @@ signatures=preprocess.signatures('your/path/to/example_signatures.csv')
The example expression matrix we provided here is a normalized example. In most scenarios, users are encouraged to preprocess raw count outputs of their sequencing data. Considering the features of scRNA-seq data, we suggest that users may follow the pre-processing code below to achieve the best performance on their scRNA-seq raw counts. The log-transformation is always suggested to avoid heavy-tailed datasets.
```{r}
#Install preprocessCore if required
source("http://bioconductor.org/biocLite.R")
biocLite("preprocessCore")
if (!requireNamespace("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("preprocessCore")
library('preprocessCore')
#Read data
exp_raw=read.csv('your/path/to/raw/expression_matrix.csv',row.names=1,stringsAsFactors = F)
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