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GWASpipeline

The goal of this project is to create a shareable GWAS pipeline. The initial focus of this effort is to define the feature list, output format and the tools/languages used in the development of this pipeline. The proposed steps in this pipeline are shown below.

  1. VCF -> GDS
  2. GDS - > PCA
  3. PCA <-> GRM
  4. GRM -> Null model + GWAS <- Phenotype
  5. GWAS -> Output
  6. Output -> Bayesian analysis -> updated output

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Pipeline for 2-step GWAS

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