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Merge pull request #389 from geneontology/suzialeksander-patch-45
Update contributing-go.md
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@@ -10,7 +10,7 @@ While most GO annotations are produced by [members of the GO Consortium](/docs/g | |
Researchers who notice either missing or inaccurate annotations for a gene or a GO term can [send this information to the GO Consortium](http://help.geneontology.org/){:target="blank"}. | ||
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### 1. Gather all necessary information | ||
- Paper citation (PMID if available) | ||
- Literature citation (PMID if available) | ||
- Description of the issue: the gene product and the term combination that you suggest be reviewed and why you believe this is incorrect | ||
- A suggestion for a solution, if possible | ||
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@@ -19,7 +19,18 @@ Researchers who notice either missing or inaccurate annotations for a gene or a | |
* Alternatively, contact the [GO helpdesk](http://help.geneontology.org/){:target="blank"} with your request. | ||
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## Contributing new GO annotations | ||
Research groups who wish to generate GO annotations, for instance new annotations for genes of a species that is not currently annotated in GO, annotating specific genes for a given biological research domain, can contribute these annotations to the GO knowledgebase. | ||
Our recommendation for annotating novel genomes is to [submit transcripts to NCBI](https://www.ncbi.nlm.nih.gov/). These submissions will reach [UniProt](https://www.uniprot.org/){:target="blank"}, where [InterPro2GO](https://www.ebi.ac.uk/GOA/InterPro2GO){:target="blank"} will automatically create high-quality ([IEA](/docs/guide-go-evidence-codes/)) GO annotations. These annotations will be made available in a future GO release. GO does not recommend that groups create their own IEAs with internal tools due to reproducibility and accuracy concerns. | ||
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Research groups who wish to generate manual GO annotations from experimental data- for instance, new annotations for genes of a species that is not currently annotated in GO, or annotating specific genes for a given biological research domain- can contribute these annotations to the GO knowledgebase. **Please contact us early in your project to establish the data exchange process between your group and GO.** GO will make sure you have access to the proper documentation and training materials to ensure your annotations meet the GO guidelines. | ||
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GO annotation files must be in [GAF 2.2](/docs/go-annotation-file-gaf-format-2.2/) and contain: | ||
- UniProt IDs, or IDs that can be mapped to UniProt, for each annotated entity | ||
- precise & informative valid GO terms for each entity, taking in to account taxon constraints and term restrictions | ||
- PMID of the published literature describing the methods and findings | ||
- a precise [evidence code](/docs/guide-go-evidence-codes/) | ||
- other mandatory elements are listed in the [GAF 2.2 documentation](/docs/go-annotation-file-gaf-format-2.2/) | ||
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Other information, such as mapping files, may be required in addition to the GAF. | ||
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## Contributing your expertise | ||
The Gene Ontology Consortium welcomes contributions from experts in any area of biology to help us improve the annotations. [Contact us](mailto:[email protected]) to start contributing to the GO annotations. | ||
The Gene Ontology Consortium welcomes contributions from experts in any area of biology to help us improve the annotations. [Contact us](mailto:[email protected]) to start contributing or improving GO annotations. |