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Note that we need to structure d-variate, d-QTL scan differently because design matrix can't easily be written as a kronecker product of two matrices. However, for d-variate, one-QTL scan, we can write X matrix I_d \otimes genoprobs
The text was updated successfully, but these errors were encountered:
I would still need to get RSS for a generalized least squares-type problem... or, I can first rotate the X matrix and Y matrix by the matrix sqrt of the inverse Sigma. I would then need to input the appropriately rotated X and Y into a function like that for multivariate regression (linked in previous comment)
Draw on C++ functions that rqtl/qtl2 uses. Also, for one-QTL, multivariate scan, use Eigen package functions: https://eigen.tuxfamily.org/dox/unsupported/group__KroneckerProduct__Module.html
Note that we need to structure d-variate, d-QTL scan differently because design matrix can't easily be written as a kronecker product of two matrices. However, for d-variate, one-QTL scan, we can write X matrix I_d \otimes genoprobs
The text was updated successfully, but these errors were encountered: