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Allele Specific QC filtering at multi-allelic sites #314

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jjfarrell opened this issue Sep 26, 2024 · 0 comments
Open

Allele Specific QC filtering at multi-allelic sites #314

jjfarrell opened this issue Sep 26, 2024 · 0 comments

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@jjfarrell
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What is the best approach for QC of multi-allelic variant in a GLnexus pVCF? If there is one high quality alternate allele and a poor quality allele at a multi-allelic site, how are they filtered properly? In GATK VQSR, there is now a Allele Specific INFO field (AS_FilterStatus) to filter on. Is there something comparable with GLnexus?

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