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There may be a sublineage of XBB.2.3 that has convergently acquired S:H47Y (BF.5/BF.7.14 ) plus a couple more of AA mutations (S:D80Y and Orf1b:A241T) , it has likely started to circulate in England, but it has originated from India.
It may be relevant cause XBB.2.3 is scoring quite high in the last #Collection24 updates
FedeGueli
changed the title
Sublineage of XBB.2.3 (S:F486P) with Orf1b:A241T,Orf7a:H47Y,S:D80Y circualting in India and Uk
Sublineage of XBB.2.3 (S:F486P) with Orf1b:A241T,Orf7a:H47Y,S:D80Y circualting in India and Uk- 80 sequences
Mar 22, 2023
There may be a sublineage of XBB.2.3 that has convergently acquired S:H47Y (BF.5/BF.7.14 ) plus a couple more of AA mutations (S:D80Y and Orf1b:A241T) , it has likely started to circulate in England, but it has originated from India.
It may be relevant cause XBB.2.3 is scoring quite high in the last #Collection24 updates
Defining mutations:
XBB.2.3 >G29706T> C6031T, C11824T, Orf1b:A241T (G14188A = NSP12_A250T) , G19254A, S:D80Y (G21800T), Orf7a:H47Y (C27532T)
Tree:
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_54e3_59aed0.json?c=gt-ORF7a_47&label=id:node_7810443
Gisaid query:NSP12_A250T ,NS7a_H47Y,Spike_D80Y
Sequences : 67 on Usher but just 59 on Gisaid:
here a 52 seqs list from CovSepctrum (filtered for good quality)
contributors (2).csv
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