BQ.1.1.32 sublineage with S:T547K (440 seqs from USA, UK, France, Germany, Canada, China)

[emily-smith1]

Description

Sublineage of: BQ.1.1.32
Earliest sequence: 2022-11-08 (USA-CA)
Most recent sequence: 2023-01-24 (USA-CA)
Countries circulating: USA, UK, France, Germany, Canada, China
GISAID query: Spike_K444T,Spike_F486V,Spike_R346T,Spike_M153I,Spike_y144del,Spike_T547K

The GISAID query returns 440 sequences, but almost half are missing from the UShER global tree. However, all sequences in GISAID receive a BQ.1.1.32 lineage assignment when uploaded to UShER.

Evidence

UShER link: https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_1a6d5_c5ce30.json?label=id:node_3342795

Annotated by Spike position 547

Zoomed in to potential sublineage

35% growth advantage worldwide for the last 3 months (BQ.1.1.32 + S:T547K)

[InfrPopGen]

Thanks for submitting. We've added lineage DT.2 with 392 newly designated sequences, and 19 updated from BQ.1.1.32. Defining mutation C23202A (S:T547K) (following G22021A (S:M153I)).