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Designate EG.5.1.19 (S:L455F, ORF1b:K1383R, ORF3a:M260K) with 140 seqs
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@corneliusroemer
corneliusroemer committed Nov 28, 2023
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2 comments on commit 0807c23

@FedeGueli
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From #2322

@AngieHinrichs
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@corneliusroemer I think many of the designated sequences added in this commit do not belong in EG.5.1.19. @aviczhl2 reported this in sars-cov-2-variants/lineage-proposals#1170. Both #2322 and the lineage_notes.txt description list three mutations past EG.5.1:

EG.5.1.19 Alias of XBB.1.9.2.5.1.19, S:L455F, ORF1b:K1383R, ORF3a:M260K

However, many of the designated sequences in lineages.csv have only ORF3a:M260K, not ORF1b:K1383R and S:L455F (for example England/CLIMB-CM7YROYU/2023|OY731700.1|2023-08-29). It might make sense to replace the current set of designated sequences for EG.5.1.19 with the set from the branch that has all 3 mutations. An example sequence at the base of that branch is Canada/ON-PHL-23-31151/2023|EPI_ISL_18304972|2023-09-13.

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