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Add Eagle2 #51851

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Nov 4, 2024
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5 changes: 5 additions & 0 deletions recipes/eagle2/0001-Use-CXX-and-flags.patch
Original file line number Diff line number Diff line change
@@ -0,0 +1,5 @@
--- src/Makefile
+++ src/Makefile
@@ -1,99 +1,99 @@
-O = DipTreePBWT.o Eagle.o EagleImpMiss.o EagleParams.o EaglePBWT.o FileUtils.o GenoData.o HapHedge.o MapInterpolater.o MemoryUtils.o NumericUtils.o StaticMultimap.o StringUtils.o SyncedVcfData.o Timer.o memcpy.o
+O = DipTreePBWT.o Eagle.o EagleImpMiss.o EagleParams.o EaglePBWT.o FileUtils.o GenoData.o HapHedge.o MapInterpolater.o MemoryUtils.o NumericUtils.o StaticMultimap.o StringUtils.o SyncedVcfData.o Timer.o
31 changes: 31 additions & 0 deletions recipes/eagle2/build.sh
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#!/bin/bash
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#set -euo pipefail

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echo "Building Eagle2 version ${PKG_VERSION}"

cd src

sed -i.bak '/memcpy.o/d' Makefile
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# Set up environment variables for building
export BOOST_INSTALL_DIR=$PREFIX
export HTSLIB_DIR=$PREFIX
export BLAS_DIR=$PREFIX/lib
export ZLIB_STATIC_DIR=$PREFIX

# Run make
make CC=${CXX} \
-e -j ${CPU_COUNT} \
CFLAGS="$CXXFLAGS -Wno-unused-result" \
BOOST_INSTALL_DIR=$BOOST_INSTALL_DIR \
HTSLIB_DIR=$HTSLIB_DIR \
BLAS_DIR=$BLAS_DIR \
ZLIB_STATIC_DIR=$ZLIB_STATIC_DIR \
LIBSTDCXX_STATIC_DIR=${PREFIX}/bin \
linking=dynamic
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echo "Installing Eagle2..."
mkdir -p "${PREFIX}/bin"
install -m 755 eagle "${PREFIX}/bin/"
echo "Eagle2 installation completed successfully"
50 changes: 50 additions & 0 deletions recipes/eagle2/meta.yaml
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{% set version = "2.4.1" %}

package:
name: eagle2
version: {{ version }}

build:
number: 0
run_exports:
- {{ pin_subpackage('eagle2', max_pin='x.x.x') }}
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source:
url: https://github.com/poruloh/Eagle/archive/refs/tags/v{{ version }}.tar.gz
sha256: 85804bfe972186ccb66e602856d6e04044302e5c0dbf9309849b0cde981e3432

requirements:
build:
- make
- {{ compiler('c') }}
- {{ compiler('cxx') }}
host:
- htslib >=1.9
- bzip2
- zlib
- boost-cpp >=1.58
- openblas >=0.2.19
run:
- {{ pin_compatible('htslib') }}
- {{ pin_compatible('bzip2') }}
- {{ pin_compatible('boost-cpp') }}
- {{ pin_compatible('zlib') }}
- {{ pin_compatible('openblas') }}
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Suggested change
run:
- {{ pin_compatible('htslib') }}
- {{ pin_compatible('bzip2') }}
- {{ pin_compatible('boost-cpp') }}
- {{ pin_compatible('zlib') }}
- {{ pin_compatible('openblas') }}

This is usually not needed, because those packages define run_exports on their own.

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Okay I will delete them

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If I remove them the boost library is not found.
I've looked in the bioconda repository and people seems to run the last four of them (they are not part of bioconda).


test:
commands:
- eagle -h
- eagle --vcfRef=example/ref.bcf --vcfTarget=example/target.vcf.gz --geneticMapFile=tables/genetic_map_hg19_example.txt.gz --outPrefix=target.phased
- eagle --bfile=example/EUR_test --geneticMapFile=USE_BIM --chrom=21 --outPrefix=phased --numThreads=4 --v1fast
about:
home: https://github.com/poruloh/Eagle
license: GPLv3
summary: The Eagle software estimates haplotype phase either within a genotyped cohort or using a phased reference panel.
description:
Eagle2 is now the default phasing method used by the Sanger and Michigan imputation servers and uses a new
very fast HMM-based algorithm that improves speed and accuracy over existing methods via two key ideas;
a new data structure based on the positional Burrows-Wheeler transform and a rapid search algorithm that
explores only the most relevant paths through the HMM. Compared to the Eagle1 algorithm, Eagle2 has similar
speed but much greater accuracy at sample sizes <50,000; as such, we have made the Eagle2 algorithm the default option.
(The Eagle1 algorithm can be accessed via the --v1 flag.) Eagle v2.3+ supports phasing sequence data with or without
a reference and also supports phasing chrX.
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