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Repository containing the code to reproduce the analyses contained in the MEFISTO manuscript

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MEFISTO applications

This repository contains application of MEFISTO to simulated and multi-modal omics data:

  • simulations: Applications to simulated data in various experiments
  • evodevo: Applications to gene expression data along development from multiple species and organs
  • microbiome: Applications to microbiome data along the first months of life in children
  • spatial: Applications to spatial transcriptomics data
  • scnmt: Applications to a scNMT-seq data

MEFISTO is implemented as part of the MOFA framework.

Please visit our webpage for more information on the framework and how to use MEFISTO with it. There you will find additional tutorials, vignettes and FAQs, including tutorials on all applications listed above.

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