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Gene-wide variation landscape #67

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gromdimon opened this issue Sep 20, 2023 · 0 comments · Fixed by #105
Closed

Gene-wide variation landscape #67

gromdimon opened this issue Sep 20, 2023 · 0 comments · Fixed by #105
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enhancement New feature or request
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@gromdimon
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Is your feature request related to a problem? Please describe.
It would be good to see the variation landscape within a gene. This should include gnomAD but also the in-house variant data. Data can be analyzed nicely with lollipop plots.

Describe the solution you'd like
Add a button that allows to see the mutational landscape of a gene in the result view. Clicking it, a modal opens that displays the variants in the background database with frequency using lollipop plots. The view should allow selecting for the appropriate transcript to plot. The view could also show the variants in gnomAD for this gene. The view could also display overlapping SVs.

Describe alternatives you've considered
N/A

Additional context
N/A

@gromdimon gromdimon added the enhancement New feature or request label Sep 20, 2023
@gromdimon gromdimon assigned gromdimon and unassigned gromdimon Sep 27, 2023
@gromdimon gromdimon added this to the 0.1.0 milestone Oct 2, 2023
holtgrewe added a commit that referenced this issue Oct 2, 2023
This provides access to all affected genes in a SV. Note that
this also changes keys from kebab-case to snake_case.
@gromdimon gromdimon linked a pull request Oct 4, 2023 that will close this issue
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